Chemometric study and optimization of heads pace solid-phase microextraction parameters for the determination of multiclass pesticide residues in processed cocoa from Nigeria using gas chromatography/mass spectrometry
Solid-phase microextraction (SPME) is a solventless sample preparation method that combines sample preparation, isolation, concentration, and enrichment into one step. A simple and effective method coupling headspace-SPME to GC/MS was developed for the analysis of chlorpyrifos, fenitrothion, endosu...
| Main Authors: | , |
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| Format: | Conference or Workshop Item |
| Language: | English |
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2014
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| Online Access: | http://eprints.um.edu.my/11418/1/0001.pdf |
| _version_ | 1825720023769939968 |
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| author | Abdulra'uf, L.B. Guan, H.T. |
| author_facet | Abdulra'uf, L.B. Guan, H.T. |
| author_sort | Abdulra'uf, L.B. |
| collection | UM |
| description | Solid-phase microextraction (SPME) is a solventless sample preparation method that combines sample preparation, isolation, concentration, and enrichment into one step. A simple and effective method coupling headspace-SPME to GC/MS
was developed for the analysis of chlorpyrifos, fenitrothion, endosulfan I, and endosulfan " pesticide residues in cocoa powder. In this study, multivariate strategy was used to determine the significance of the factors affecting the SPME of the pesticides using a Plackett-Burman design, and the significant factors were optimized using central composite design. The analytes were extracted with 100 pm polydimethylsiloxane fibers according
to the factorial design matrix and desorbed into a GC/MS instrument The developed method was applied for the analysis of a cocoa powder sample, and it exhibited good figures of merit for the analytical methodology. Using the optimized
conditions, the linearity ranged from 2.5 to 500 pg/kg (R2> 0.99) using an internal standard calibration method, and the average recoveries were between 75 and 95%, with RSD values between 3.8 and 9.7%. |
| first_indexed | 2024-03-06T05:28:40Z |
| format | Conference or Workshop Item |
| id | um.eprints-11418 |
| institution | Universiti Malaya |
| language | English |
| last_indexed | 2024-03-06T05:28:40Z |
| publishDate | 2014 |
| record_format | dspace |
| spelling | um.eprints-114182014-12-18T03:52:16Z http://eprints.um.edu.my/11418/ Chemometric study and optimization of heads pace solid-phase microextraction parameters for the determination of multiclass pesticide residues in processed cocoa from Nigeria using gas chromatography/mass spectrometry Abdulra'uf, L.B. Guan, H.T. QD Chemistry Solid-phase microextraction (SPME) is a solventless sample preparation method that combines sample preparation, isolation, concentration, and enrichment into one step. A simple and effective method coupling headspace-SPME to GC/MS was developed for the analysis of chlorpyrifos, fenitrothion, endosulfan I, and endosulfan " pesticide residues in cocoa powder. In this study, multivariate strategy was used to determine the significance of the factors affecting the SPME of the pesticides using a Plackett-Burman design, and the significant factors were optimized using central composite design. The analytes were extracted with 100 pm polydimethylsiloxane fibers according to the factorial design matrix and desorbed into a GC/MS instrument The developed method was applied for the analysis of a cocoa powder sample, and it exhibited good figures of merit for the analytical methodology. Using the optimized conditions, the linearity ranged from 2.5 to 500 pg/kg (R2> 0.99) using an internal standard calibration method, and the average recoveries were between 75 and 95%, with RSD values between 3.8 and 9.7%. 2014-11 Conference or Workshop Item PeerReviewed application/pdf en http://eprints.um.edu.my/11418/1/0001.pdf Abdulra'uf, L.B. and Guan, H.T. (2014) Chemometric study and optimization of heads pace solid-phase microextraction parameters for the determination of multiclass pesticide residues in processed cocoa from Nigeria using gas chromatography/mass spectrometry. In: Vietnam Malaysia International Chemical Congress (VMICC), 07-09 Nov 2014, Hanoi, Vietnam.. (Submitted) |
| spellingShingle | QD Chemistry Abdulra'uf, L.B. Guan, H.T. Chemometric study and optimization of heads pace solid-phase microextraction parameters for the determination of multiclass pesticide residues in processed cocoa from Nigeria using gas chromatography/mass spectrometry |
| title | Chemometric study and optimization of heads pace solid-phase microextraction parameters for the determination of multiclass pesticide residues in processed cocoa from Nigeria using gas chromatography/mass spectrometry |
| title_full | Chemometric study and optimization of heads pace solid-phase microextraction parameters for the determination of multiclass pesticide residues in processed cocoa from Nigeria using gas chromatography/mass spectrometry |
| title_fullStr | Chemometric study and optimization of heads pace solid-phase microextraction parameters for the determination of multiclass pesticide residues in processed cocoa from Nigeria using gas chromatography/mass spectrometry |
| title_full_unstemmed | Chemometric study and optimization of heads pace solid-phase microextraction parameters for the determination of multiclass pesticide residues in processed cocoa from Nigeria using gas chromatography/mass spectrometry |
| title_short | Chemometric study and optimization of heads pace solid-phase microextraction parameters for the determination of multiclass pesticide residues in processed cocoa from Nigeria using gas chromatography/mass spectrometry |
| title_sort | chemometric study and optimization of heads pace solid phase microextraction parameters for the determination of multiclass pesticide residues in processed cocoa from nigeria using gas chromatography mass spectrometry |
| topic | QD Chemistry |
| url | http://eprints.um.edu.my/11418/1/0001.pdf |
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