Non-fatal paliperidone overdose: A case report

Paliperidone, a novel serotonin and dopamine antagonist, is one of the newest atypical antipsychotics on the market. It is an orally administered drug that is indicated for the treatment of schizophrenia, and is considered to be safe and well tolerated. A 37-year-old female with a long-standing hist...

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Main Authors: Gill, J.S., Pillai, S.K., Koh, O.H., Jambunathan, S.
Format: Article
Published: Turkiye Sinir Ve Ruh Sagligi Dernegi 2010
Subjects:
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author Gill, J.S.
Pillai, S.K.
Koh, O.H.
Jambunathan, S.
author_facet Gill, J.S.
Pillai, S.K.
Koh, O.H.
Jambunathan, S.
author_sort Gill, J.S.
collection UM
description Paliperidone, a novel serotonin and dopamine antagonist, is one of the newest atypical antipsychotics on the market. It is an orally administered drug that is indicated for the treatment of schizophrenia, and is considered to be safe and well tolerated. A 37-year-old female with a long-standing history of schizophrenia had been taking paliperidone 12 mg d-1 for about 1.5 years. She overdosed on a total of 756 mg of paliperidone in response to auditory command hallucinations. She was promptly hospitalized, and fortunately did not suffer any major adverse clinical events, adverse laboratory parameters, or long lasting sequelae. Herein we discuss the inherent characteristics of paliperidone that limit the danger associated with overdosing.
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spelling um.eprints-119462015-01-13T06:48:11Z http://eprints.um.edu.my/11946/ Non-fatal paliperidone overdose: A case report Gill, J.S. Pillai, S.K. Koh, O.H. Jambunathan, S. R Medicine Paliperidone, a novel serotonin and dopamine antagonist, is one of the newest atypical antipsychotics on the market. It is an orally administered drug that is indicated for the treatment of schizophrenia, and is considered to be safe and well tolerated. A 37-year-old female with a long-standing history of schizophrenia had been taking paliperidone 12 mg d-1 for about 1.5 years. She overdosed on a total of 756 mg of paliperidone in response to auditory command hallucinations. She was promptly hospitalized, and fortunately did not suffer any major adverse clinical events, adverse laboratory parameters, or long lasting sequelae. Herein we discuss the inherent characteristics of paliperidone that limit the danger associated with overdosing. Turkiye Sinir Ve Ruh Sagligi Dernegi 2010 Article PeerReviewed Gill, J.S. and Pillai, S.K. and Koh, O.H. and Jambunathan, S. (2010) Non-fatal paliperidone overdose: A case report. Turk Psikiyatri Dergisi, 21 (4). pp. 331-333.
spellingShingle R Medicine
Gill, J.S.
Pillai, S.K.
Koh, O.H.
Jambunathan, S.
Non-fatal paliperidone overdose: A case report
title Non-fatal paliperidone overdose: A case report
title_full Non-fatal paliperidone overdose: A case report
title_fullStr Non-fatal paliperidone overdose: A case report
title_full_unstemmed Non-fatal paliperidone overdose: A case report
title_short Non-fatal paliperidone overdose: A case report
title_sort non fatal paliperidone overdose a case report
topic R Medicine
work_keys_str_mv AT gilljs nonfatalpaliperidoneoverdoseacasereport
AT pillaisk nonfatalpaliperidoneoverdoseacasereport
AT kohoh nonfatalpaliperidoneoverdoseacasereport
AT jambunathans nonfatalpaliperidoneoverdoseacasereport