Identification of copy number alterations by array comparative genomic hybridization in patients with late chronic or accelerated phase chronic myeloid leukemia treated with imatinib mesylate

The outcome of treating chronic myeloid leukemia (CML) with imatinib mesylate (IM) is inferior when therapy is commenced in late chronic or accelerated phase as compared to early chronic phase. This may be attributed to additional genomic alterations that accumulate during disease progression. We so...

詳細記述

書誌詳細
主要な著者: Nadarajan, V.S., Phan, C.L., Ang, C.H., Liang, K.L., Gan, G.G., Bee, P.C., Zakaria, Z.
フォーマット: 論文
出版事項: Springer Verlag (Germany) 2011
主題: