Unusual indole alkaloid-pyrrole, -pyrone, and -carbamic acid adducts from Alstonia angustifolia
Three unusual natural products, viz., alstopirocine, a macroline alkaloid incorporating a substituted pyrrole moiety, pleiomaltinine, an alkaloid-pyrone adduct, and pleiomalicine, an alkaloid-carbamic acid adduct, were isolated from the Malayan Alstonia angustifolia. The alkaloid moiety in alstopiro...
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Elsevier
2010
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| author | Tan, Shin-Jowl Choo, Yeun-Mun Thomas, N.F. Robinson, W.T. Komiyama, K. Kam, Toh-Seok |
| author_facet | Tan, Shin-Jowl Choo, Yeun-Mun Thomas, N.F. Robinson, W.T. Komiyama, K. Kam, Toh-Seok |
| author_sort | Tan, Shin-Jowl |
| collection | UM |
| description | Three unusual natural products, viz., alstopirocine, a macroline alkaloid incorporating a substituted pyrrole moiety, pleiomaltinine, an alkaloid-pyrone adduct, and pleiomalicine, an alkaloid-carbamic acid adduct, were isolated from the Malayan Alstonia angustifolia. The alkaloid moiety in alstopirocine was alstomicine while that in pleiomaltinine and pleiomalicine was pleiocarpamine. The structures were determined by spectroscopic methods and in the case of pleiomaltinine, confirmed by X-ray diffraction analysis. Possible biogenetic pathways to these unusual compounds are presented. (C) 2010 Elsevier Ltd. All rights reserved. |
| first_indexed | 2024-03-06T05:30:54Z |
| format | Article |
| id | um.eprints-12335 |
| institution | Universiti Malaya |
| last_indexed | 2024-03-06T05:30:54Z |
| publishDate | 2010 |
| publisher | Elsevier |
| record_format | dspace |
| spelling | um.eprints-123352015-01-22T02:09:17Z http://eprints.um.edu.my/12335/ Unusual indole alkaloid-pyrrole, -pyrone, and -carbamic acid adducts from Alstonia angustifolia Tan, Shin-Jowl Choo, Yeun-Mun Thomas, N.F. Robinson, W.T. Komiyama, K. Kam, Toh-Seok Q Science (General) Three unusual natural products, viz., alstopirocine, a macroline alkaloid incorporating a substituted pyrrole moiety, pleiomaltinine, an alkaloid-pyrone adduct, and pleiomalicine, an alkaloid-carbamic acid adduct, were isolated from the Malayan Alstonia angustifolia. The alkaloid moiety in alstopirocine was alstomicine while that in pleiomaltinine and pleiomalicine was pleiocarpamine. The structures were determined by spectroscopic methods and in the case of pleiomaltinine, confirmed by X-ray diffraction analysis. Possible biogenetic pathways to these unusual compounds are presented. (C) 2010 Elsevier Ltd. All rights reserved. Elsevier 2010 Article PeerReviewed Tan, Shin-Jowl and Choo, Yeun-Mun and Thomas, N.F. and Robinson, W.T. and Komiyama, K. and Kam, Toh-Seok (2010) Unusual indole alkaloid-pyrrole, -pyrone, and -carbamic acid adducts from Alstonia angustifolia. Tetrahedron, 66 (39). pp. 7799-7806. |
| spellingShingle | Q Science (General) Tan, Shin-Jowl Choo, Yeun-Mun Thomas, N.F. Robinson, W.T. Komiyama, K. Kam, Toh-Seok Unusual indole alkaloid-pyrrole, -pyrone, and -carbamic acid adducts from Alstonia angustifolia |
| title | Unusual indole alkaloid-pyrrole, -pyrone, and -carbamic acid adducts from Alstonia angustifolia |
| title_full | Unusual indole alkaloid-pyrrole, -pyrone, and -carbamic acid adducts from Alstonia angustifolia |
| title_fullStr | Unusual indole alkaloid-pyrrole, -pyrone, and -carbamic acid adducts from Alstonia angustifolia |
| title_full_unstemmed | Unusual indole alkaloid-pyrrole, -pyrone, and -carbamic acid adducts from Alstonia angustifolia |
| title_short | Unusual indole alkaloid-pyrrole, -pyrone, and -carbamic acid adducts from Alstonia angustifolia |
| title_sort | unusual indole alkaloid pyrrole pyrone and carbamic acid adducts from alstonia angustifolia |
| topic | Q Science (General) |
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