Idiopathic paroxysmal kinesigenic dyskinesia in Malaysia, a multi-racial Southeast Asian country

Paroxysmal kinesigenic dyskinesia is a rare disorder, and there are few reports of Asian patients with this condition. We reviewed the clinical features of all patients with idiopathic paroxysmal kinesigenic dyskinesia (PKD) seen at a major neurological centre in Malaysia. The charts of 11 patients...

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Main Authors: Tai, Mei-Ling.S., Lim, Shen-Yang, Tan, C.T.
Format: Article
Published: Elsevier 2010
Subjects:
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author Tai, Mei-Ling.S.
Lim, Shen-Yang
Tan, C.T.
author_facet Tai, Mei-Ling.S.
Lim, Shen-Yang
Tan, C.T.
author_sort Tai, Mei-Ling.S.
collection UM
description Paroxysmal kinesigenic dyskinesia is a rare disorder, and there are few reports of Asian patients with this condition. We reviewed the clinical features of all patients with idiopathic paroxysmal kinesigenic dyskinesia (PKD) seen at a major neurological centre in Malaysia. The charts of 11 patients with idiopathic PKD seen between 1995 and 2008 were reviewed retrospectively. The male:female ratio was 9:2. Ten patients were of Chinese ethnicity, and one was Malay. Three patients (from two families) had a family history of PKD. The involuntary movement was dystonia in 73% of patients. In one patient, attacks were precipitated by vestibular stimulation. One patient had generalized epilepsy. Another patient who did not have epilepsy demonstrated epileptiform discharges. Only slightly over one-quarter of patients had a positive family history. Males, and people of Chinese ancestry, seem to be affected more frequently by MD in certain Asian populations. (C) 2010 Elsevier Ltd. All rights reserved.
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spelling um.eprints-126422015-02-09T04:49:16Z http://eprints.um.edu.my/12642/ Idiopathic paroxysmal kinesigenic dyskinesia in Malaysia, a multi-racial Southeast Asian country Tai, Mei-Ling.S. Lim, Shen-Yang Tan, C.T. R Medicine Paroxysmal kinesigenic dyskinesia is a rare disorder, and there are few reports of Asian patients with this condition. We reviewed the clinical features of all patients with idiopathic paroxysmal kinesigenic dyskinesia (PKD) seen at a major neurological centre in Malaysia. The charts of 11 patients with idiopathic PKD seen between 1995 and 2008 were reviewed retrospectively. The male:female ratio was 9:2. Ten patients were of Chinese ethnicity, and one was Malay. Three patients (from two families) had a family history of PKD. The involuntary movement was dystonia in 73% of patients. In one patient, attacks were precipitated by vestibular stimulation. One patient had generalized epilepsy. Another patient who did not have epilepsy demonstrated epileptiform discharges. Only slightly over one-quarter of patients had a positive family history. Males, and people of Chinese ancestry, seem to be affected more frequently by MD in certain Asian populations. (C) 2010 Elsevier Ltd. All rights reserved. Elsevier 2010 Article PeerReviewed Tai, Mei-Ling.S. and Lim, Shen-Yang and Tan, C.T. (2010) Idiopathic paroxysmal kinesigenic dyskinesia in Malaysia, a multi-racial Southeast Asian country. Journal of Clinical Neuroscience, 17 (8). pp. 1089-1090.
spellingShingle R Medicine
Tai, Mei-Ling.S.
Lim, Shen-Yang
Tan, C.T.
Idiopathic paroxysmal kinesigenic dyskinesia in Malaysia, a multi-racial Southeast Asian country
title Idiopathic paroxysmal kinesigenic dyskinesia in Malaysia, a multi-racial Southeast Asian country
title_full Idiopathic paroxysmal kinesigenic dyskinesia in Malaysia, a multi-racial Southeast Asian country
title_fullStr Idiopathic paroxysmal kinesigenic dyskinesia in Malaysia, a multi-racial Southeast Asian country
title_full_unstemmed Idiopathic paroxysmal kinesigenic dyskinesia in Malaysia, a multi-racial Southeast Asian country
title_short Idiopathic paroxysmal kinesigenic dyskinesia in Malaysia, a multi-racial Southeast Asian country
title_sort idiopathic paroxysmal kinesigenic dyskinesia in malaysia a multi racial southeast asian country
topic R Medicine
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AT limshenyang idiopathicparoxysmalkinesigenicdyskinesiainmalaysiaamultiracialsoutheastasiancountry
AT tanct idiopathicparoxysmalkinesigenicdyskinesiainmalaysiaamultiracialsoutheastasiancountry