Synthesis and characteristics of cryogels of chitosan crosslinked by glutaric aldehyde
The mechanism of cryotropic gelation in moderately frozen solutions of chitosan crosslinked by glutaric aldehyde is studied. Chitosan cryogels with large pores are synthesized at a low content of crosslinking agent in the reaction mixture or under conditions that do not lead to gelation at temperatu...
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| Format: | Article |
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Maik Nauka/Interperiodica/Springer
2010
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| author | Nikonorov, V.V. Ivanov, R.V. Kil'deeva, N.R. Bulatnikova, L.N. Lozinskii, V.I. |
| author_facet | Nikonorov, V.V. Ivanov, R.V. Kil'deeva, N.R. Bulatnikova, L.N. Lozinskii, V.I. |
| author_sort | Nikonorov, V.V. |
| collection | UM |
| description | The mechanism of cryotropic gelation in moderately frozen solutions of chitosan crosslinked by glutaric aldehyde is studied. Chitosan cryogels with large pores are synthesized at a low content of crosslinking agent in the reaction mixture or under conditions that do not lead to gelation at temperatures above 0 degrees C. The dependences of the yield of gel fractions, the degree of swelling of the polymer phase of cryogels, and the hydrodynamic characteristics of cryogels on the temperature of synthesis are shown to be extremal. This result may be explained by the competition between the cryoconcentration of reagents in the nonfrozen liquid microphase, which assists the development of a crosslinked polymer network, and such factors as an increase in the viscosity of the reaction mixture and a reduced reagent mobility, which prevent gelation. The morphology of chitosan cryogels is studied, and the character of the macroporous structure of the samples prepared at different temperatures is shown to exert a stronger effect on the hydrodynamic characteristics of a cryogel than the degree of swelling of crosslinked polymers in the walls of its macropores. |
| first_indexed | 2024-03-06T05:31:41Z |
| format | Article |
| id | um.eprints-12668 |
| institution | Universiti Malaya |
| last_indexed | 2024-03-06T05:31:41Z |
| publishDate | 2010 |
| publisher | Maik Nauka/Interperiodica/Springer |
| record_format | dspace |
| spelling | um.eprints-126682015-02-10T07:43:12Z http://eprints.um.edu.my/12668/ Synthesis and characteristics of cryogels of chitosan crosslinked by glutaric aldehyde Nikonorov, V.V. Ivanov, R.V. Kil'deeva, N.R. Bulatnikova, L.N. Lozinskii, V.I. Q Science (General) The mechanism of cryotropic gelation in moderately frozen solutions of chitosan crosslinked by glutaric aldehyde is studied. Chitosan cryogels with large pores are synthesized at a low content of crosslinking agent in the reaction mixture or under conditions that do not lead to gelation at temperatures above 0 degrees C. The dependences of the yield of gel fractions, the degree of swelling of the polymer phase of cryogels, and the hydrodynamic characteristics of cryogels on the temperature of synthesis are shown to be extremal. This result may be explained by the competition between the cryoconcentration of reagents in the nonfrozen liquid microphase, which assists the development of a crosslinked polymer network, and such factors as an increase in the viscosity of the reaction mixture and a reduced reagent mobility, which prevent gelation. The morphology of chitosan cryogels is studied, and the character of the macroporous structure of the samples prepared at different temperatures is shown to exert a stronger effect on the hydrodynamic characteristics of a cryogel than the degree of swelling of crosslinked polymers in the walls of its macropores. Maik Nauka/Interperiodica/Springer 2010 Article PeerReviewed Nikonorov, V.V. and Ivanov, R.V. and Kil'deeva, N.R. and Bulatnikova, L.N. and Lozinskii, V.I. (2010) Synthesis and characteristics of cryogels of chitosan crosslinked by glutaric aldehyde. Polymer Science Series A, 52 (8). pp. 828-834. |
| spellingShingle | Q Science (General) Nikonorov, V.V. Ivanov, R.V. Kil'deeva, N.R. Bulatnikova, L.N. Lozinskii, V.I. Synthesis and characteristics of cryogels of chitosan crosslinked by glutaric aldehyde |
| title | Synthesis and characteristics of cryogels of chitosan crosslinked by glutaric aldehyde |
| title_full | Synthesis and characteristics of cryogels of chitosan crosslinked by glutaric aldehyde |
| title_fullStr | Synthesis and characteristics of cryogels of chitosan crosslinked by glutaric aldehyde |
| title_full_unstemmed | Synthesis and characteristics of cryogels of chitosan crosslinked by glutaric aldehyde |
| title_short | Synthesis and characteristics of cryogels of chitosan crosslinked by glutaric aldehyde |
| title_sort | synthesis and characteristics of cryogels of chitosan crosslinked by glutaric aldehyde |
| topic | Q Science (General) |
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