Effects of Malaysian medicinal plants on macrophage functions in vitro study
The effects of aqueous leaf extract of eight local medicinal plant species on the phagocytic and antibacterial potential of mouse peritoneal macrophages against Staphylococcus aureus were investigated. The mouse macrophages cultures were incubated with various concentrations (0.2, 0.4, 0.8, 1.6 and...
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| Format: | Article |
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Academic Journals
2010
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| author | Al-Bayaty, F.H. Mohamed, M.A.A. Abu Hassan, I. Hussein, S.F. |
| author_facet | Al-Bayaty, F.H. Mohamed, M.A.A. Abu Hassan, I. Hussein, S.F. |
| author_sort | Al-Bayaty, F.H. |
| collection | UM |
| description | The effects of aqueous leaf extract of eight local medicinal plant species on the phagocytic and antibacterial potential of mouse peritoneal macrophages against Staphylococcus aureus were investigated. The mouse macrophages cultures were incubated with various concentrations (0.2, 0.4, 0.8, 1.6 and 3.2 mg/ml) of plant extracts in different sets of test tubes at 37 C for one hour. After incubation, their phagocytic and antibacterial effects on S. aureus were determined. Results have shown that the extracts of Orthosiphon stramineus, and Andrographis paniculata inhibited the phagocytic activity and intracellular killing of S. aureus compared with controls. Activated cells had more phagocytic activity and intracellular killing than normal macrophages. There were no differences in the viability of macrophage cells treated with extracts and those without extracts (control). |
| first_indexed | 2024-03-06T05:31:43Z |
| format | Article |
| id | um.eprints-12685 |
| institution | Universiti Malaya |
| last_indexed | 2024-03-06T05:31:43Z |
| publishDate | 2010 |
| publisher | Academic Journals |
| record_format | dspace |
| spelling | um.eprints-126852015-02-11T06:34:23Z http://eprints.um.edu.my/12685/ Effects of Malaysian medicinal plants on macrophage functions in vitro study Al-Bayaty, F.H. Mohamed, M.A.A. Abu Hassan, I. Hussein, S.F. R Medicine The effects of aqueous leaf extract of eight local medicinal plant species on the phagocytic and antibacterial potential of mouse peritoneal macrophages against Staphylococcus aureus were investigated. The mouse macrophages cultures were incubated with various concentrations (0.2, 0.4, 0.8, 1.6 and 3.2 mg/ml) of plant extracts in different sets of test tubes at 37 C for one hour. After incubation, their phagocytic and antibacterial effects on S. aureus were determined. Results have shown that the extracts of Orthosiphon stramineus, and Andrographis paniculata inhibited the phagocytic activity and intracellular killing of S. aureus compared with controls. Activated cells had more phagocytic activity and intracellular killing than normal macrophages. There were no differences in the viability of macrophage cells treated with extracts and those without extracts (control). Academic Journals 2010 Article PeerReviewed Al-Bayaty, F.H. and Mohamed, M.A.A. and Abu Hassan, I. and Hussein, S.F. (2010) Effects of Malaysian medicinal plants on macrophage functions in vitro study. Journal of Medicinal Plants Research, 4 (14). pp. 1472-1476. |
| spellingShingle | R Medicine Al-Bayaty, F.H. Mohamed, M.A.A. Abu Hassan, I. Hussein, S.F. Effects of Malaysian medicinal plants on macrophage functions in vitro study |
| title | Effects of Malaysian medicinal plants on macrophage functions in vitro study |
| title_full | Effects of Malaysian medicinal plants on macrophage functions in vitro study |
| title_fullStr | Effects of Malaysian medicinal plants on macrophage functions in vitro study |
| title_full_unstemmed | Effects of Malaysian medicinal plants on macrophage functions in vitro study |
| title_short | Effects of Malaysian medicinal plants on macrophage functions in vitro study |
| title_sort | effects of malaysian medicinal plants on macrophage functions in vitro study |
| topic | R Medicine |
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