Phyllanthus spp. induces selective growth inhibition of PC-3 and MeWo human cancer cells through modulation of cell cycle and induction of apoptosis.
Phyllanthus plant exerts its growth inhibition effect in a selective manner towards cancer cells through the modulation of cell cycle and induction of apoptosis via caspases activation in melanoma and prostate cancer cells. Hence, Phyllanthus may be sourced for the development of a potent apoptosis-...
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| Format: | Article |
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Public Library of Science
2010
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| author | Tang, Y. Jaganath, I.B. Sekaran, S.D. |
| author_facet | Tang, Y. Jaganath, I.B. Sekaran, S.D. |
| author_sort | Tang, Y. |
| collection | UM |
| description | Phyllanthus plant exerts its growth inhibition effect in a selective manner towards cancer cells through the modulation of cell cycle and induction of apoptosis via caspases activation in melanoma and prostate cancer cells. Hence, Phyllanthus may be sourced for the development of a potent apoptosis-inducing anticancer agent. |
| first_indexed | 2024-03-06T05:05:50Z |
| format | Article |
| id | um.eprints-1276 |
| institution | Universiti Malaya |
| last_indexed | 2024-03-06T05:05:50Z |
| publishDate | 2010 |
| publisher | Public Library of Science |
| record_format | dspace |
| spelling | um.eprints-12762017-07-04T02:09:41Z http://eprints.um.edu.my/1276/ Phyllanthus spp. induces selective growth inhibition of PC-3 and MeWo human cancer cells through modulation of cell cycle and induction of apoptosis. Tang, Y. Jaganath, I.B. Sekaran, S.D. R Medicine Phyllanthus plant exerts its growth inhibition effect in a selective manner towards cancer cells through the modulation of cell cycle and induction of apoptosis via caspases activation in melanoma and prostate cancer cells. Hence, Phyllanthus may be sourced for the development of a potent apoptosis-inducing anticancer agent. Public Library of Science 2010 Article PeerReviewed Tang, Y. and Jaganath, I.B. and Sekaran, S.D. (2010) Phyllanthus spp. induces selective growth inhibition of PC-3 and MeWo human cancer cells through modulation of cell cycle and induction of apoptosis. PLoS ONE, 5 (9). e12644. ISSN 1932-6203, DOI 20838625. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2935893/ 20838625 |
| spellingShingle | R Medicine Tang, Y. Jaganath, I.B. Sekaran, S.D. Phyllanthus spp. induces selective growth inhibition of PC-3 and MeWo human cancer cells through modulation of cell cycle and induction of apoptosis. |
| title | Phyllanthus spp. induces selective growth inhibition of PC-3 and MeWo human cancer cells through modulation of cell cycle and induction of apoptosis. |
| title_full | Phyllanthus spp. induces selective growth inhibition of PC-3 and MeWo human cancer cells through modulation of cell cycle and induction of apoptosis. |
| title_fullStr | Phyllanthus spp. induces selective growth inhibition of PC-3 and MeWo human cancer cells through modulation of cell cycle and induction of apoptosis. |
| title_full_unstemmed | Phyllanthus spp. induces selective growth inhibition of PC-3 and MeWo human cancer cells through modulation of cell cycle and induction of apoptosis. |
| title_short | Phyllanthus spp. induces selective growth inhibition of PC-3 and MeWo human cancer cells through modulation of cell cycle and induction of apoptosis. |
| title_sort | phyllanthus spp induces selective growth inhibition of pc 3 and mewo human cancer cells through modulation of cell cycle and induction of apoptosis |
| topic | R Medicine |
| work_keys_str_mv | AT tangy phyllanthussppinducesselectivegrowthinhibitionofpc3andmewohumancancercellsthroughmodulationofcellcycleandinductionofapoptosis AT jaganathib phyllanthussppinducesselectivegrowthinhibitionofpc3andmewohumancancercellsthroughmodulationofcellcycleandinductionofapoptosis AT sekaransd phyllanthussppinducesselectivegrowthinhibitionofpc3andmewohumancancercellsthroughmodulationofcellcycleandinductionofapoptosis |