Immunological diagnosis of human angiostrongyliasis due to Angiostrongylus cantonensis (Nematoda: Angiostrongylidae)
Angiostrongylus cantonensis-associated eosinophilic meningitis in humans has been commonly reported worldwide. However parasitologically confirmed cases are not common, as the parasite has been recovered only infrequently from the cerebrospinal fluid of patients. The potential value of immunodiagnos...
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| Format: | Article |
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Elsevier
2009
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| _version_ | 1796946562504458240 |
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| author | Eamsobhana, Praphathip Yong, Hoi Sen |
| author_facet | Eamsobhana, Praphathip Yong, Hoi Sen |
| author_sort | Eamsobhana, Praphathip |
| collection | UM |
| description | Angiostrongylus cantonensis-associated eosinophilic meningitis in humans has been commonly reported worldwide. However parasitologically confirmed cases are not common, as the parasite has been recovered only infrequently from the cerebrospinal fluid of patients. The potential value of immunodiagnosis is therefore self-evident. Immunological tests can also help in the differential diagnosis of parasitic (particularly helminths) infections that cause eosinophilic meningitis. This paper summarizes the state of and advances in the immunological diagnosis of human angiostrongyliasis due to Angiostrongylus (= Parastrongylus) cantonensis. A specific antigen is available for the definitive diagnosis and unequivocal differentiation of eosinophilic meningitis due to helminth infections. Rapid diagnostic kits based on dot-blot ELISA have been developed and have proved to be simple, effective, and economical for field use. |
| first_indexed | 2024-03-06T05:33:40Z |
| format | Article |
| id | um.eprints-13392 |
| institution | Universiti Malaya |
| last_indexed | 2024-03-06T05:33:40Z |
| publishDate | 2009 |
| publisher | Elsevier |
| record_format | dspace |
| spelling | um.eprints-133922019-12-05T04:21:36Z http://eprints.um.edu.my/13392/ Immunological diagnosis of human angiostrongyliasis due to Angiostrongylus cantonensis (Nematoda: Angiostrongylidae) Eamsobhana, Praphathip Yong, Hoi Sen Q Science (General) QH Natural history Angiostrongylus cantonensis-associated eosinophilic meningitis in humans has been commonly reported worldwide. However parasitologically confirmed cases are not common, as the parasite has been recovered only infrequently from the cerebrospinal fluid of patients. The potential value of immunodiagnosis is therefore self-evident. Immunological tests can also help in the differential diagnosis of parasitic (particularly helminths) infections that cause eosinophilic meningitis. This paper summarizes the state of and advances in the immunological diagnosis of human angiostrongyliasis due to Angiostrongylus (= Parastrongylus) cantonensis. A specific antigen is available for the definitive diagnosis and unequivocal differentiation of eosinophilic meningitis due to helminth infections. Rapid diagnostic kits based on dot-blot ELISA have been developed and have proved to be simple, effective, and economical for field use. Elsevier 2009-07 Article PeerReviewed Eamsobhana, Praphathip and Yong, Hoi Sen (2009) Immunological diagnosis of human angiostrongyliasis due to Angiostrongylus cantonensis (Nematoda: Angiostrongylidae). International Journal of Infectious Diseases, 13 (4). pp. 425-431. ISSN 1201-9712, DOI https://doi.org/10.1016/j.ijid.2008.09.021 <https://doi.org/10.1016/j.ijid.2008.09.021>. http://www.sciencedirect.com/science/article/pii/S1201971208016834 http://dx.doi.org/10.1016/j.ijid.2008.09.021 |
| spellingShingle | Q Science (General) QH Natural history Eamsobhana, Praphathip Yong, Hoi Sen Immunological diagnosis of human angiostrongyliasis due to Angiostrongylus cantonensis (Nematoda: Angiostrongylidae) |
| title | Immunological diagnosis of human angiostrongyliasis due to Angiostrongylus cantonensis (Nematoda: Angiostrongylidae) |
| title_full | Immunological diagnosis of human angiostrongyliasis due to Angiostrongylus cantonensis (Nematoda: Angiostrongylidae) |
| title_fullStr | Immunological diagnosis of human angiostrongyliasis due to Angiostrongylus cantonensis (Nematoda: Angiostrongylidae) |
| title_full_unstemmed | Immunological diagnosis of human angiostrongyliasis due to Angiostrongylus cantonensis (Nematoda: Angiostrongylidae) |
| title_short | Immunological diagnosis of human angiostrongyliasis due to Angiostrongylus cantonensis (Nematoda: Angiostrongylidae) |
| title_sort | immunological diagnosis of human angiostrongyliasis due to angiostrongylus cantonensis nematoda angiostrongylidae |
| topic | Q Science (General) QH Natural history |
| work_keys_str_mv | AT eamsobhanapraphathip immunologicaldiagnosisofhumanangiostrongyliasisduetoangiostrongyluscantonensisnematodaangiostrongylidae AT yonghoisen immunologicaldiagnosisofhumanangiostrongyliasisduetoangiostrongyluscantonensisnematodaangiostrongylidae |