Platelet-rich plasma injections for the treatment of hamstring injuries: a randomized controlled trial

Background: A hamstring injury is one of the most common types of injury affecting athletes. Despite this, the optimal management of hamstring muscle injuries is not yet defined. The effect of autologous platelet-rich plasma (PRP) therapy on the recovery of hamstring injuries is unclear. Purpose:...

Full description

Bibliographic Details
Main Authors: Hamid, M.S.A., Mohamed Ali, M.R., Yusof, A., George, J., Lee, P.C.
Format: Article
Published: SAGE Publications (UK and US) 2014
Subjects:
_version_ 1825720496212148224
author Hamid, M.S.A.
Mohamed Ali, M.R.
Yusof, A.
George, J.
Lee, P.C.
author_facet Hamid, M.S.A.
Mohamed Ali, M.R.
Yusof, A.
George, J.
Lee, P.C.
author_sort Hamid, M.S.A.
collection UM
description Background: A hamstring injury is one of the most common types of injury affecting athletes. Despite this, the optimal management of hamstring muscle injuries is not yet defined. The effect of autologous platelet-rich plasma (PRP) therapy on the recovery of hamstring injuries is unclear. Purpose: To investigate the effect of a single PRP injection in the treatment of grade 2 hamstring muscle injuries. Study Design: Randomized controlled trial; Level of evidence, 2. Methods: Twenty-eight patients diagnosed with an acute hamstring injury were randomly allocated to autologous PRP therapy combined with a rehabilitation program or a rehabilitation program only. The primary outcome of this study was time to return to play. In addition, changes in pain severity and pain interference scores over time were examined. Results: Patients in the PRP group achieved full recovery significantly earlier than controls (P = .02). The mean time to return to play was 42.5 ± 20.6 days in the control group and 26.7 ± 7.0 days in the PRP group. Significantly lower pain severity scores were observed in the PRP group throughout the study. However, no significant difference in the pain interference score was found between the 2 groups. Conclusion: A single autologous PRP injection combined with a rehabilitation program was significantly more effective in treating hamstring injuries than a rehabilitation program alone.
first_indexed 2024-03-06T05:36:02Z
format Article
id um.eprints-14295
institution Universiti Malaya
last_indexed 2024-03-06T05:36:02Z
publishDate 2014
publisher SAGE Publications (UK and US)
record_format dspace
spelling um.eprints-142952015-10-23T07:10:03Z http://eprints.um.edu.my/14295/ Platelet-rich plasma injections for the treatment of hamstring injuries: a randomized controlled trial Hamid, M.S.A. Mohamed Ali, M.R. Yusof, A. George, J. Lee, P.C. GV Recreation Leisure R Medicine Background: A hamstring injury is one of the most common types of injury affecting athletes. Despite this, the optimal management of hamstring muscle injuries is not yet defined. The effect of autologous platelet-rich plasma (PRP) therapy on the recovery of hamstring injuries is unclear. Purpose: To investigate the effect of a single PRP injection in the treatment of grade 2 hamstring muscle injuries. Study Design: Randomized controlled trial; Level of evidence, 2. Methods: Twenty-eight patients diagnosed with an acute hamstring injury were randomly allocated to autologous PRP therapy combined with a rehabilitation program or a rehabilitation program only. The primary outcome of this study was time to return to play. In addition, changes in pain severity and pain interference scores over time were examined. Results: Patients in the PRP group achieved full recovery significantly earlier than controls (P = .02). The mean time to return to play was 42.5 ± 20.6 days in the control group and 26.7 ± 7.0 days in the PRP group. Significantly lower pain severity scores were observed in the PRP group throughout the study. However, no significant difference in the pain interference score was found between the 2 groups. Conclusion: A single autologous PRP injection combined with a rehabilitation program was significantly more effective in treating hamstring injuries than a rehabilitation program alone. SAGE Publications (UK and US) 2014-10 Article PeerReviewed Hamid, M.S.A. and Mohamed Ali, M.R. and Yusof, A. and George, J. and Lee, P.C. (2014) Platelet-rich plasma injections for the treatment of hamstring injuries: a randomized controlled trial. The American Journal of Sports Medicine, 42 (10). pp. 2410-2418. ISSN 0363-5465, DOI https://doi.org/10.1177/0363546514541540 <https://doi.org/10.1177/0363546514541540 >. http://ajs.sagepub.com/content/42/10/2410.long doi: 10.1177/0363546514541540
spellingShingle GV Recreation Leisure
R Medicine
Hamid, M.S.A.
Mohamed Ali, M.R.
Yusof, A.
George, J.
Lee, P.C.
Platelet-rich plasma injections for the treatment of hamstring injuries: a randomized controlled trial
title Platelet-rich plasma injections for the treatment of hamstring injuries: a randomized controlled trial
title_full Platelet-rich plasma injections for the treatment of hamstring injuries: a randomized controlled trial
title_fullStr Platelet-rich plasma injections for the treatment of hamstring injuries: a randomized controlled trial
title_full_unstemmed Platelet-rich plasma injections for the treatment of hamstring injuries: a randomized controlled trial
title_short Platelet-rich plasma injections for the treatment of hamstring injuries: a randomized controlled trial
title_sort platelet rich plasma injections for the treatment of hamstring injuries a randomized controlled trial
topic GV Recreation Leisure
R Medicine
work_keys_str_mv AT hamidmsa plateletrichplasmainjectionsforthetreatmentofhamstringinjuriesarandomizedcontrolledtrial
AT mohamedalimr plateletrichplasmainjectionsforthetreatmentofhamstringinjuriesarandomizedcontrolledtrial
AT yusofa plateletrichplasmainjectionsforthetreatmentofhamstringinjuriesarandomizedcontrolledtrial
AT georgej plateletrichplasmainjectionsforthetreatmentofhamstringinjuriesarandomizedcontrolledtrial
AT leepc plateletrichplasmainjectionsforthetreatmentofhamstringinjuriesarandomizedcontrolledtrial