Qatchewing and periodontal pathogens in health and disease: Further evidence for a prebiotic-like effect
Aim. Qat chewing has been reported to induce subgingival microbial shifts suggestive of prebiotic-like properties. The objective here was to assess the effect of qat chewing on a panel of classical and new putative periopathogens in health and periodontitis. Materials and Methods. 40 qat chewers and...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Hindawi Publishing Corporation
2015
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| Online Access: | http://eprints.um.edu.my/14376/1/291305_%282%29.pdf |
| _version_ | 1825720511083053056 |
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| author | Al-alimi, A. Taiyeb Ali, T.B. Jaafar, N. Al-hebshi, N.N. |
| author_facet | Al-alimi, A. Taiyeb Ali, T.B. Jaafar, N. Al-hebshi, N.N. |
| author_sort | Al-alimi, A. |
| collection | UM |
| description | Aim. Qat chewing has been reported to induce subgingival microbial shifts suggestive of prebiotic-like properties. The objective here was to assess the effect of qat chewing on a panel of classical and new putative periopathogens in health and periodontitis. Materials and Methods. 40 qat chewers and 40 nonchewers, equally stratified by periodontal health status, were recruited. Taqman, real-time PCR was used to quantify total bacteria, Porphyromonas gingivalis, Tannerella forsythia, Treponema denticola, Parvimonas micra, Filifactor alocis, Synergistetes, and TM7s in pooled subgingival biofilm samples. Differences in microbial parameters between the study groups were analysed using ordinal regression. Results. In health, the qat chewers harboured significantly lower relative counts of P. gingivalis, T. forsythia, Synergistetes, and TM7s after adjustment for multiple comparisons (P <= 0.007). At nominal significance level, they also carried lower counts of TM7s and P. micra (P <= 0.05). In periodontitis, the chewers had lower counts of all taxa; however, only T. denticola withstood correction for multiple comparisons (P <= 0.0063). Conclusions. Qat chewing is associated with lower proportions of periopathogens, particularly in subjects with healthy periodontium, which supports previous reports of its prebiotic-like properties. This potentially beneficial biological effect can be exploited by attempting to isolate the active fraction. |
| first_indexed | 2024-03-06T05:36:16Z |
| format | Article |
| id | um.eprints-14376 |
| institution | Universiti Malaya |
| language | English |
| last_indexed | 2024-03-06T05:36:16Z |
| publishDate | 2015 |
| publisher | Hindawi Publishing Corporation |
| record_format | dspace |
| spelling | um.eprints-143762017-07-12T09:25:08Z http://eprints.um.edu.my/14376/ Qatchewing and periodontal pathogens in health and disease: Further evidence for a prebiotic-like effect Al-alimi, A. Taiyeb Ali, T.B. Jaafar, N. Al-hebshi, N.N. RK Dentistry Aim. Qat chewing has been reported to induce subgingival microbial shifts suggestive of prebiotic-like properties. The objective here was to assess the effect of qat chewing on a panel of classical and new putative periopathogens in health and periodontitis. Materials and Methods. 40 qat chewers and 40 nonchewers, equally stratified by periodontal health status, were recruited. Taqman, real-time PCR was used to quantify total bacteria, Porphyromonas gingivalis, Tannerella forsythia, Treponema denticola, Parvimonas micra, Filifactor alocis, Synergistetes, and TM7s in pooled subgingival biofilm samples. Differences in microbial parameters between the study groups were analysed using ordinal regression. Results. In health, the qat chewers harboured significantly lower relative counts of P. gingivalis, T. forsythia, Synergistetes, and TM7s after adjustment for multiple comparisons (P <= 0.007). At nominal significance level, they also carried lower counts of TM7s and P. micra (P <= 0.05). In periodontitis, the chewers had lower counts of all taxa; however, only T. denticola withstood correction for multiple comparisons (P <= 0.0063). Conclusions. Qat chewing is associated with lower proportions of periopathogens, particularly in subjects with healthy periodontium, which supports previous reports of its prebiotic-like properties. This potentially beneficial biological effect can be exploited by attempting to isolate the active fraction. Hindawi Publishing Corporation 2015 Article PeerReviewed application/pdf en http://eprints.um.edu.my/14376/1/291305_%282%29.pdf Al-alimi, A. and Taiyeb Ali, T.B. and Jaafar, N. and Al-hebshi, N.N. (2015) Qatchewing and periodontal pathogens in health and disease: Further evidence for a prebiotic-like effect. BioMed Research International. ISSN 2314-6133, DOI https://doi.org/10.1155/2015/291305 <https://doi.org/10.1155/2015/291305>. http://dx.doi.org/10.1155/2015/291305 10.1155/2015/291305 |
| spellingShingle | RK Dentistry Al-alimi, A. Taiyeb Ali, T.B. Jaafar, N. Al-hebshi, N.N. Qatchewing and periodontal pathogens in health and disease: Further evidence for a prebiotic-like effect |
| title | Qatchewing and periodontal pathogens in health and disease: Further evidence for a prebiotic-like effect |
| title_full | Qatchewing and periodontal pathogens in health and disease: Further evidence for a prebiotic-like effect |
| title_fullStr | Qatchewing and periodontal pathogens in health and disease: Further evidence for a prebiotic-like effect |
| title_full_unstemmed | Qatchewing and periodontal pathogens in health and disease: Further evidence for a prebiotic-like effect |
| title_short | Qatchewing and periodontal pathogens in health and disease: Further evidence for a prebiotic-like effect |
| title_sort | qatchewing and periodontal pathogens in health and disease further evidence for a prebiotic like effect |
| topic | RK Dentistry |
| url | http://eprints.um.edu.my/14376/1/291305_%282%29.pdf |
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