Antibacterial Activity of Leaf Extracts of Baeckea frutescens against Methicillin-Resistant Staphylococcus aureus

This study was based on screening antibacterial activity of the ethanol extract of Baeckea frutescens L. against MRSA clinical isolates, analyzes the potential antibacterial compound, and assesses the cytotoxicity effect of the extract in tissue culture. Leaves of Baeckea frutescens L. were shade dr...

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Main Authors: Razmavar, S., Abdulla, M.A., Ismail, S., Hassandarvish, P.
Format: Article
Published: Hindawi Publishing Corporation 2014
Subjects:
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author Razmavar, S.
Abdulla, M.A.
Ismail, S.
Hassandarvish, P.
author_facet Razmavar, S.
Abdulla, M.A.
Ismail, S.
Hassandarvish, P.
author_sort Razmavar, S.
collection UM
description This study was based on screening antibacterial activity of the ethanol extract of Baeckea frutescens L. against MRSA clinical isolates, analyzes the potential antibacterial compound, and assesses the cytotoxicity effect of the extract in tissue culture. Leaves of Baeckea frutescens L. were shade dried, powdered, and extracted using solvent ethanol. Preliminary phytochemical screening of the crude extracts revealed the presence of alkaloids, flavonoids, steroids, terpenoids, phenols, and carbohydrates. The presence of these bioactive constituents is related to the antibacterial activity of the plant. Disc diffusion method revealed a high degree of activity against microorganisms. The results confirm that Baeckea frutescens L. can be used as a source of drugs to fight infections caused by susceptible bacteria.
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spelling um.eprints-145272015-11-05T09:13:10Z http://eprints.um.edu.my/14527/ Antibacterial Activity of Leaf Extracts of Baeckea frutescens against Methicillin-Resistant Staphylococcus aureus Razmavar, S. Abdulla, M.A. Ismail, S. Hassandarvish, P. Q Science (General) QH Natural history This study was based on screening antibacterial activity of the ethanol extract of Baeckea frutescens L. against MRSA clinical isolates, analyzes the potential antibacterial compound, and assesses the cytotoxicity effect of the extract in tissue culture. Leaves of Baeckea frutescens L. were shade dried, powdered, and extracted using solvent ethanol. Preliminary phytochemical screening of the crude extracts revealed the presence of alkaloids, flavonoids, steroids, terpenoids, phenols, and carbohydrates. The presence of these bioactive constituents is related to the antibacterial activity of the plant. Disc diffusion method revealed a high degree of activity against microorganisms. The results confirm that Baeckea frutescens L. can be used as a source of drugs to fight infections caused by susceptible bacteria. Hindawi Publishing Corporation 2014 Article PeerReviewed Razmavar, S. and Abdulla, M.A. and Ismail, S. and Hassandarvish, P. (2014) Antibacterial Activity of Leaf Extracts of Baeckea frutescens against Methicillin-Resistant Staphylococcus aureus. BioMed Research International, 2014. pp. 1-5. ISSN 2314-6133, DOI https://doi.org/10.1155/2014/521287 <https://doi.org/10.1155/2014/521287>. http://www.hindawi.com/journals/bmri/2014/521287/ http://dx.doi.org/10.1155/2014/521287
spellingShingle Q Science (General)
QH Natural history
Razmavar, S.
Abdulla, M.A.
Ismail, S.
Hassandarvish, P.
Antibacterial Activity of Leaf Extracts of Baeckea frutescens against Methicillin-Resistant Staphylococcus aureus
title Antibacterial Activity of Leaf Extracts of Baeckea frutescens against Methicillin-Resistant Staphylococcus aureus
title_full Antibacterial Activity of Leaf Extracts of Baeckea frutescens against Methicillin-Resistant Staphylococcus aureus
title_fullStr Antibacterial Activity of Leaf Extracts of Baeckea frutescens against Methicillin-Resistant Staphylococcus aureus
title_full_unstemmed Antibacterial Activity of Leaf Extracts of Baeckea frutescens against Methicillin-Resistant Staphylococcus aureus
title_short Antibacterial Activity of Leaf Extracts of Baeckea frutescens against Methicillin-Resistant Staphylococcus aureus
title_sort antibacterial activity of leaf extracts of baeckea frutescens against methicillin resistant staphylococcus aureus
topic Q Science (General)
QH Natural history
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AT ismails antibacterialactivityofleafextractsofbaeckeafrutescensagainstmethicillinresistantstaphylococcusaureus
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