Antibacterial Activity of Leaf Extracts of Baeckea frutescens against Methicillin-Resistant Staphylococcus aureus
This study was based on screening antibacterial activity of the ethanol extract of Baeckea frutescens L. against MRSA clinical isolates, analyzes the potential antibacterial compound, and assesses the cytotoxicity effect of the extract in tissue culture. Leaves of Baeckea frutescens L. were shade dr...
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Hindawi Publishing Corporation
2014
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author | Razmavar, S. Abdulla, M.A. Ismail, S. Hassandarvish, P. |
author_facet | Razmavar, S. Abdulla, M.A. Ismail, S. Hassandarvish, P. |
author_sort | Razmavar, S. |
collection | UM |
description | This study was based on screening antibacterial activity of the ethanol extract of Baeckea frutescens L. against MRSA clinical isolates, analyzes the potential antibacterial compound, and assesses the cytotoxicity effect of the extract in tissue culture. Leaves of Baeckea frutescens L. were shade dried, powdered, and extracted using solvent ethanol. Preliminary phytochemical screening of the crude extracts revealed the presence of alkaloids, flavonoids, steroids, terpenoids, phenols, and carbohydrates. The presence of these bioactive constituents is related to the antibacterial activity of the plant. Disc diffusion method revealed a high degree of activity against microorganisms. The results confirm that Baeckea frutescens L. can be used as a source of drugs to fight infections caused by susceptible bacteria. |
first_indexed | 2024-03-06T05:36:40Z |
format | Article |
id | um.eprints-14527 |
institution | Universiti Malaya |
last_indexed | 2024-03-06T05:36:40Z |
publishDate | 2014 |
publisher | Hindawi Publishing Corporation |
record_format | dspace |
spelling | um.eprints-145272015-11-05T09:13:10Z http://eprints.um.edu.my/14527/ Antibacterial Activity of Leaf Extracts of Baeckea frutescens against Methicillin-Resistant Staphylococcus aureus Razmavar, S. Abdulla, M.A. Ismail, S. Hassandarvish, P. Q Science (General) QH Natural history This study was based on screening antibacterial activity of the ethanol extract of Baeckea frutescens L. against MRSA clinical isolates, analyzes the potential antibacterial compound, and assesses the cytotoxicity effect of the extract in tissue culture. Leaves of Baeckea frutescens L. were shade dried, powdered, and extracted using solvent ethanol. Preliminary phytochemical screening of the crude extracts revealed the presence of alkaloids, flavonoids, steroids, terpenoids, phenols, and carbohydrates. The presence of these bioactive constituents is related to the antibacterial activity of the plant. Disc diffusion method revealed a high degree of activity against microorganisms. The results confirm that Baeckea frutescens L. can be used as a source of drugs to fight infections caused by susceptible bacteria. Hindawi Publishing Corporation 2014 Article PeerReviewed Razmavar, S. and Abdulla, M.A. and Ismail, S. and Hassandarvish, P. (2014) Antibacterial Activity of Leaf Extracts of Baeckea frutescens against Methicillin-Resistant Staphylococcus aureus. BioMed Research International, 2014. pp. 1-5. ISSN 2314-6133, DOI https://doi.org/10.1155/2014/521287 <https://doi.org/10.1155/2014/521287>. http://www.hindawi.com/journals/bmri/2014/521287/ http://dx.doi.org/10.1155/2014/521287 |
spellingShingle | Q Science (General) QH Natural history Razmavar, S. Abdulla, M.A. Ismail, S. Hassandarvish, P. Antibacterial Activity of Leaf Extracts of Baeckea frutescens against Methicillin-Resistant Staphylococcus aureus |
title | Antibacterial Activity of Leaf Extracts of Baeckea frutescens against Methicillin-Resistant Staphylococcus aureus |
title_full | Antibacterial Activity of Leaf Extracts of Baeckea frutescens against Methicillin-Resistant Staphylococcus aureus |
title_fullStr | Antibacterial Activity of Leaf Extracts of Baeckea frutescens against Methicillin-Resistant Staphylococcus aureus |
title_full_unstemmed | Antibacterial Activity of Leaf Extracts of Baeckea frutescens against Methicillin-Resistant Staphylococcus aureus |
title_short | Antibacterial Activity of Leaf Extracts of Baeckea frutescens against Methicillin-Resistant Staphylococcus aureus |
title_sort | antibacterial activity of leaf extracts of baeckea frutescens against methicillin resistant staphylococcus aureus |
topic | Q Science (General) QH Natural history |
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