Enhanced production of periplasmic interferon alpha-2b by Escherichia coli using ion-exchange resin for in situ removal of acetate in the culture
The possibility of using in situ addition of anion-exchange resin for the removal of acetate in the culture aimed at improving growth of E. coli and expression of periplasmic human interferon-alpha ab (PrIFN-alpha 2b) was studied in shake flask culture and stirred tank bioreactor. Different types of...
| Príomhchruthaitheoirí: | , , , , |
|---|---|
| Formáid: | Alt |
| Foilsithe / Cruthaithe: |
Elsevier
2011
|
| Ábhair: |