Enhanced production of periplasmic interferon alpha-2b by Escherichia coli using ion-exchange resin for in situ removal of acetate in the culture
The possibility of using in situ addition of anion-exchange resin for the removal of acetate in the culture aimed at improving growth of E. coli and expression of periplasmic human interferon-alpha ab (PrIFN-alpha 2b) was studied in shake flask culture and stirred tank bioreactor. Different types of...
| Үндсэн зохиолчид: | , , , , |
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| Формат: | Өгүүллэг |
| Хэвлэсэн: |
Elsevier
2011
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| Нөхцлүүд: |