Bisleuconothine A, an eburnane-aspidosperma bisindole alkaloid from Leuconotis griffithii

A new bisindole alkaloid, bisleuconothine A(1) consisting of an eburnane-aspidosperma type skeleton, was isolated from the bark of Leuconotis griffithii. The structure including absolute stereochemistry was elucidated on the basis of 2D NMR data and X-ray analysis. Bisleuconothine A(1) showed cell g...

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Main Authors: Hirasawa, Y., Shoji, T., Arai, T., Nugroho, A.E., Deguchi, J., Hosoya, T., Uchiyama, N., Goda, Y., Awang, K., Hadi, A.H.A., Shiro, M., Morita, H.
Format: Article
Published: Elsevier 2010
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author Hirasawa, Y.
Shoji, T.
Arai, T.
Nugroho, A.E.
Deguchi, J.
Hosoya, T.
Uchiyama, N.
Goda, Y.
Awang, K.
Hadi, A.H.A.
Shiro, M.
Morita, H.
author_facet Hirasawa, Y.
Shoji, T.
Arai, T.
Nugroho, A.E.
Deguchi, J.
Hosoya, T.
Uchiyama, N.
Goda, Y.
Awang, K.
Hadi, A.H.A.
Shiro, M.
Morita, H.
author_sort Hirasawa, Y.
collection UM
description A new bisindole alkaloid, bisleuconothine A(1) consisting of an eburnane-aspidosperma type skeleton, was isolated from the bark of Leuconotis griffithii. The structure including absolute stereochemistry was elucidated on the basis of 2D NMR data and X-ray analysis. Bisleuconothine A(1) showed cell growth inhibitory activity against various human cancer cell lines. (C) 2010 Elsevier Ltd. All rights reserved.
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spelling um.eprints-149772015-12-01T00:38:15Z http://eprints.um.edu.my/14977/ Bisleuconothine A, an eburnane-aspidosperma bisindole alkaloid from Leuconotis griffithii Hirasawa, Y. Shoji, T. Arai, T. Nugroho, A.E. Deguchi, J. Hosoya, T. Uchiyama, N. Goda, Y. Awang, K. Hadi, A.H.A. Shiro, M. Morita, H. Q Science (General) A new bisindole alkaloid, bisleuconothine A(1) consisting of an eburnane-aspidosperma type skeleton, was isolated from the bark of Leuconotis griffithii. The structure including absolute stereochemistry was elucidated on the basis of 2D NMR data and X-ray analysis. Bisleuconothine A(1) showed cell growth inhibitory activity against various human cancer cell lines. (C) 2010 Elsevier Ltd. All rights reserved. Elsevier 2010 Article PeerReviewed Hirasawa, Y. and Shoji, T. and Arai, T. and Nugroho, A.E. and Deguchi, J. and Hosoya, T. and Uchiyama, N. and Goda, Y. and Awang, K. and Hadi, A.H.A. and Shiro, M. and Morita, H. (2010) Bisleuconothine A, an eburnane-aspidosperma bisindole alkaloid from Leuconotis griffithii. Bioorganic & Medicinal Chemistry Letters, 20 (6). pp. 2021-2024.
spellingShingle Q Science (General)
Hirasawa, Y.
Shoji, T.
Arai, T.
Nugroho, A.E.
Deguchi, J.
Hosoya, T.
Uchiyama, N.
Goda, Y.
Awang, K.
Hadi, A.H.A.
Shiro, M.
Morita, H.
Bisleuconothine A, an eburnane-aspidosperma bisindole alkaloid from Leuconotis griffithii
title Bisleuconothine A, an eburnane-aspidosperma bisindole alkaloid from Leuconotis griffithii
title_full Bisleuconothine A, an eburnane-aspidosperma bisindole alkaloid from Leuconotis griffithii
title_fullStr Bisleuconothine A, an eburnane-aspidosperma bisindole alkaloid from Leuconotis griffithii
title_full_unstemmed Bisleuconothine A, an eburnane-aspidosperma bisindole alkaloid from Leuconotis griffithii
title_short Bisleuconothine A, an eburnane-aspidosperma bisindole alkaloid from Leuconotis griffithii
title_sort bisleuconothine a an eburnane aspidosperma bisindole alkaloid from leuconotis griffithii
topic Q Science (General)
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