Alcohol and the developing fetus--a review

Fetal alcohol syndrome (FAS) is a collection of signs and symptoms seen in some children exposed to alcohol in the prenatal period. It is characterized mainly by physical and mental retardation, craniofacial anomalies and minor joint abnormalities. However, with the increasing incidence of FAS, ther...

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Main Author: Chaudhuri, J.D.
Format: Article
Published: Medical Science International Publishing 2000
Subjects:
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author Chaudhuri, J.D.
author_facet Chaudhuri, J.D.
author_sort Chaudhuri, J.D.
collection UM
description Fetal alcohol syndrome (FAS) is a collection of signs and symptoms seen in some children exposed to alcohol in the prenatal period. It is characterized mainly by physical and mental retardation, craniofacial anomalies and minor joint abnormalities. However, with the increasing incidence of FAS, there is a great variation in the clinical features of FAS. This article describes in detail these clinical features. Due to ethical reasons it is not possible to perform experiments on pregnant women. Hence to study the effects of alcohol, various animal and avian experimental models have been chosen. The various experimental findings and human correlation are described. The exact mechanism by which alcohol induces its teratogenic effects is not known. The possible mechanisms are discussed. Measures to prevent the occurrence of FAS have been suggested.
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spelling um.eprints-15482018-10-26T03:35:29Z http://eprints.um.edu.my/1548/ Alcohol and the developing fetus--a review Chaudhuri, J.D. R Medicine Fetal alcohol syndrome (FAS) is a collection of signs and symptoms seen in some children exposed to alcohol in the prenatal period. It is characterized mainly by physical and mental retardation, craniofacial anomalies and minor joint abnormalities. However, with the increasing incidence of FAS, there is a great variation in the clinical features of FAS. This article describes in detail these clinical features. Due to ethical reasons it is not possible to perform experiments on pregnant women. Hence to study the effects of alcohol, various animal and avian experimental models have been chosen. The various experimental findings and human correlation are described. The exact mechanism by which alcohol induces its teratogenic effects is not known. The possible mechanisms are discussed. Measures to prevent the occurrence of FAS have been suggested. Medical Science International Publishing 2000-09 Article PeerReviewed Chaudhuri, J.D. (2000) Alcohol and the developing fetus--a review. Medical Science Monitor, 6 (5). pp. 1031-41. ISSN 1234-1010, DOI 11208451. http://www.ncbi.nlm.nih.gov/pubmed/11208451 11208451
spellingShingle R Medicine
Chaudhuri, J.D.
Alcohol and the developing fetus--a review
title Alcohol and the developing fetus--a review
title_full Alcohol and the developing fetus--a review
title_fullStr Alcohol and the developing fetus--a review
title_full_unstemmed Alcohol and the developing fetus--a review
title_short Alcohol and the developing fetus--a review
title_sort alcohol and the developing fetus a review
topic R Medicine
work_keys_str_mv AT chaudhurijd alcoholandthedevelopingfetusareview