Acute retinal necrosis by cytomegalovirus in an immunocompetent adult: case report and review of the literature.

A rare case of acute retinal necrosis caused by cytomegalovirus in an immunocompetent adult, diagnosed by polymerase chain reaction of vitreous aspirate, with good visual outcome after intravitreal and intravenous ganciclovir and oral prednisolone therapy, is reported. A 50-year-old healthy lady pre...

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Main Authors: Tajunisah, I., Reddy, S.C., Tan, L.H.
Format: Article
Published: Kluwer (now part of Springer) 2009
Subjects:
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author Tajunisah, I.
Reddy, S.C.
Tan, L.H.
author_facet Tajunisah, I.
Reddy, S.C.
Tan, L.H.
author_sort Tajunisah, I.
collection UM
description A rare case of acute retinal necrosis caused by cytomegalovirus in an immunocompetent adult, diagnosed by polymerase chain reaction of vitreous aspirate, with good visual outcome after intravitreal and intravenous ganciclovir and oral prednisolone therapy, is reported. A 50-year-old healthy lady presented with redness and diminution of vision in her right eye of 10 days duration. She had anterior chamber inflammation, marked vitritis, and anterior retinal necrosis in the right eye. Blood and other investigations did not reveal any infectious diseases and HIV testing was negative. The retinal lesions and panuveitis resolved with treatment. Two months later she developed retinal detachment which was treated successfully. The best-corrected vision was 6/12 in the right eye. Seven cases of cytomegalovirus ocular infection in immunocompetent healthy adults, reported in the literature, were reviewed. The different presentations of this disease and the importance of suspecting this causative agent are highlighted.
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spelling um.eprints-16542017-07-08T04:27:21Z http://eprints.um.edu.my/1654/ Acute retinal necrosis by cytomegalovirus in an immunocompetent adult: case report and review of the literature. Tajunisah, I. Reddy, S.C. Tan, L.H. R Medicine A rare case of acute retinal necrosis caused by cytomegalovirus in an immunocompetent adult, diagnosed by polymerase chain reaction of vitreous aspirate, with good visual outcome after intravitreal and intravenous ganciclovir and oral prednisolone therapy, is reported. A 50-year-old healthy lady presented with redness and diminution of vision in her right eye of 10 days duration. She had anterior chamber inflammation, marked vitritis, and anterior retinal necrosis in the right eye. Blood and other investigations did not reveal any infectious diseases and HIV testing was negative. The retinal lesions and panuveitis resolved with treatment. Two months later she developed retinal detachment which was treated successfully. The best-corrected vision was 6/12 in the right eye. Seven cases of cytomegalovirus ocular infection in immunocompetent healthy adults, reported in the literature, were reviewed. The different presentations of this disease and the importance of suspecting this causative agent are highlighted. Kluwer (now part of Springer) 2009-04 Article PeerReviewed Tajunisah, I. and Reddy, S.C. and Tan, L.H. (2009) Acute retinal necrosis by cytomegalovirus in an immunocompetent adult: case report and review of the literature. International Ophthalmology, 29 (2). pp. 85-90. ISSN 0165-5701, DOI 18026692. http://www.ncbi.nlm.nih.gov/pubmed/18026692 18026692
spellingShingle R Medicine
Tajunisah, I.
Reddy, S.C.
Tan, L.H.
Acute retinal necrosis by cytomegalovirus in an immunocompetent adult: case report and review of the literature.
title Acute retinal necrosis by cytomegalovirus in an immunocompetent adult: case report and review of the literature.
title_full Acute retinal necrosis by cytomegalovirus in an immunocompetent adult: case report and review of the literature.
title_fullStr Acute retinal necrosis by cytomegalovirus in an immunocompetent adult: case report and review of the literature.
title_full_unstemmed Acute retinal necrosis by cytomegalovirus in an immunocompetent adult: case report and review of the literature.
title_short Acute retinal necrosis by cytomegalovirus in an immunocompetent adult: case report and review of the literature.
title_sort acute retinal necrosis by cytomegalovirus in an immunocompetent adult case report and review of the literature
topic R Medicine
work_keys_str_mv AT tajunisahi acuteretinalnecrosisbycytomegalovirusinanimmunocompetentadultcasereportandreviewoftheliterature
AT reddysc acuteretinalnecrosisbycytomegalovirusinanimmunocompetentadultcasereportandreviewoftheliterature
AT tanlh acuteretinalnecrosisbycytomegalovirusinanimmunocompetentadultcasereportandreviewoftheliterature