Carpal bone segmentation using fully convolutional neural network

Background: Bone Age Assessment (BAA) refers to a clinical procedure that aims to identify a discrepancy between biological and chronological age of an individual by assessing the bone age growth. Currently, there are two main methods of executing BAA which are known as Greulich-Pyle and Tanner-Whit...

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Main Authors: Liang, Kim Meng, Khalil, Azira, Nizar, Muhammad Hanif Ahmad, Nisham, Maryam Kamarun, Pingguan-Murphy, Belinda, Hum, Yan Chai, Salim, Maheza Irna Mohamad, Lai, Khin Wee
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Published: Bentham Science Publishers 2019
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author Liang, Kim Meng
Khalil, Azira
Nizar, Muhammad Hanif Ahmad
Nisham, Maryam Kamarun
Pingguan-Murphy, Belinda
Hum, Yan Chai
Salim, Maheza Irna Mohamad
Lai, Khin Wee
author_facet Liang, Kim Meng
Khalil, Azira
Nizar, Muhammad Hanif Ahmad
Nisham, Maryam Kamarun
Pingguan-Murphy, Belinda
Hum, Yan Chai
Salim, Maheza Irna Mohamad
Lai, Khin Wee
author_sort Liang, Kim Meng
collection UM
description Background: Bone Age Assessment (BAA) refers to a clinical procedure that aims to identify a discrepancy between biological and chronological age of an individual by assessing the bone age growth. Currently, there are two main methods of executing BAA which are known as Greulich-Pyle and Tanner-Whitehouse techniques. Both techniques involve a manual and qualitative assessment of hand and wrist radiographs, resulting in intra and inter-operator variability accuracy and time-consuming. An automatic segmentation can be applied to the radiographs, providing the physician with more accurate delineation of the carpal bone and accurate quantitative analysis. Methods: In this study, we proposed an image feature extraction technique based on image segmentation with the fully convolutional neural network with eight stride pixel (FCN-8). A total of 290 radiographic images including both female and the male subject of age ranging from 0 to 18 were manually segmented and trained using FCN-8. Results and Conclusion: The results exhibit a high training accuracy value of 99.68% and a loss rate of 0.008619 for 50 epochs of training. The experiments compared 58 images against the gold standard ground truth images. The accuracy of our fully automated segmentation technique is 0.78 ± 0.06, 1.56 ±0.30 mm and 98.02% in terms of Dice Coefficient, Hausdorff Distance, and overall qualitative carpal recognition accuracy, respectively. © 2019 Bentham Science Publishers.
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spelling um.eprints-166922020-03-17T03:04:16Z http://eprints.um.edu.my/16692/ Carpal bone segmentation using fully convolutional neural network Liang, Kim Meng Khalil, Azira Nizar, Muhammad Hanif Ahmad Nisham, Maryam Kamarun Pingguan-Murphy, Belinda Hum, Yan Chai Salim, Maheza Irna Mohamad Lai, Khin Wee R Medicine Background: Bone Age Assessment (BAA) refers to a clinical procedure that aims to identify a discrepancy between biological and chronological age of an individual by assessing the bone age growth. Currently, there are two main methods of executing BAA which are known as Greulich-Pyle and Tanner-Whitehouse techniques. Both techniques involve a manual and qualitative assessment of hand and wrist radiographs, resulting in intra and inter-operator variability accuracy and time-consuming. An automatic segmentation can be applied to the radiographs, providing the physician with more accurate delineation of the carpal bone and accurate quantitative analysis. Methods: In this study, we proposed an image feature extraction technique based on image segmentation with the fully convolutional neural network with eight stride pixel (FCN-8). A total of 290 radiographic images including both female and the male subject of age ranging from 0 to 18 were manually segmented and trained using FCN-8. Results and Conclusion: The results exhibit a high training accuracy value of 99.68% and a loss rate of 0.008619 for 50 epochs of training. The experiments compared 58 images against the gold standard ground truth images. The accuracy of our fully automated segmentation technique is 0.78 ± 0.06, 1.56 ±0.30 mm and 98.02% in terms of Dice Coefficient, Hausdorff Distance, and overall qualitative carpal recognition accuracy, respectively. © 2019 Bentham Science Publishers. Bentham Science Publishers 2019 Article PeerReviewed Liang, Kim Meng and Khalil, Azira and Nizar, Muhammad Hanif Ahmad and Nisham, Maryam Kamarun and Pingguan-Murphy, Belinda and Hum, Yan Chai and Salim, Maheza Irna Mohamad and Lai, Khin Wee (2019) Carpal bone segmentation using fully convolutional neural network. Current Medical Imaging, 15 (10). pp. 983-989. ISSN 1573-4056, DOI https://doi.org/10.2174/1573405615666190724101600 <https://doi.org/10.2174/1573405615666190724101600>. https://doi.org/10.2174/1573405615666190724101600 doi:10.2174/1573405615666190724101600
spellingShingle R Medicine
Liang, Kim Meng
Khalil, Azira
Nizar, Muhammad Hanif Ahmad
Nisham, Maryam Kamarun
Pingguan-Murphy, Belinda
Hum, Yan Chai
Salim, Maheza Irna Mohamad
Lai, Khin Wee
Carpal bone segmentation using fully convolutional neural network
title Carpal bone segmentation using fully convolutional neural network
title_full Carpal bone segmentation using fully convolutional neural network
title_fullStr Carpal bone segmentation using fully convolutional neural network
title_full_unstemmed Carpal bone segmentation using fully convolutional neural network
title_short Carpal bone segmentation using fully convolutional neural network
title_sort carpal bone segmentation using fully convolutional neural network
topic R Medicine
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