Bilateral thalamic internal medullary lamina involvement in a case of dengue encephalitis

There are 50-100 million dengue infections each year, but dengue encephalitis is relatively uncommon. The aetiology of neuronal injury is proposed to be due to direct viral neurotropism or host immune response-mediated inflammation causing neuronal damage. We report a case of severe dengue encephali...

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Main Authors: Ahmad, S.B., Cheong, C.S., Lim, S.Y., Rahmat, K., Rozalli, F.I., Sekaran, S.D., Sulaiman, H., Ponnampalavanar, S., Lim, K.S., Tan, C.T.
Format: Article
Published: ASEAN Neurological Association 2016
Subjects:
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author Ahmad, S.B.
Cheong, C.S.
Lim, S.Y.
Rahmat, K.
Rozalli, F.I.
Sekaran, S.D.
Sulaiman, H.
Ponnampalavanar, S.
Lim, K.S.
Tan, C.T.
author_facet Ahmad, S.B.
Cheong, C.S.
Lim, S.Y.
Rahmat, K.
Rozalli, F.I.
Sekaran, S.D.
Sulaiman, H.
Ponnampalavanar, S.
Lim, K.S.
Tan, C.T.
author_sort Ahmad, S.B.
collection UM
description There are 50-100 million dengue infections each year, but dengue encephalitis is relatively uncommon. The aetiology of neuronal injury is proposed to be due to direct viral neurotropism or host immune response-mediated inflammation causing neuronal damage. We report a case of severe dengue encephalitis, presenting during the acute viraemic phase of the disease. This was associated with inflammation and haemorrhage of the internal medullary lamina of both thalami which, to our knowledge, has not yet been reported in other infections of the central nervous system.
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spelling um.eprints-181332017-11-07T03:57:21Z http://eprints.um.edu.my/18133/ Bilateral thalamic internal medullary lamina involvement in a case of dengue encephalitis Ahmad, S.B. Cheong, C.S. Lim, S.Y. Rahmat, K. Rozalli, F.I. Sekaran, S.D. Sulaiman, H. Ponnampalavanar, S. Lim, K.S. Tan, C.T. R Medicine There are 50-100 million dengue infections each year, but dengue encephalitis is relatively uncommon. The aetiology of neuronal injury is proposed to be due to direct viral neurotropism or host immune response-mediated inflammation causing neuronal damage. We report a case of severe dengue encephalitis, presenting during the acute viraemic phase of the disease. This was associated with inflammation and haemorrhage of the internal medullary lamina of both thalami which, to our knowledge, has not yet been reported in other infections of the central nervous system. ASEAN Neurological Association 2016 Article PeerReviewed Ahmad, S.B. and Cheong, C.S. and Lim, S.Y. and Rahmat, K. and Rozalli, F.I. and Sekaran, S.D. and Sulaiman, H. and Ponnampalavanar, S. and Lim, K.S. and Tan, C.T. (2016) Bilateral thalamic internal medullary lamina involvement in a case of dengue encephalitis. Neurology Asia, 21 (4). pp. 375-379. ISSN 1823-6138, https://www.neurology-asia.org/articles/neuroasia-2016-21(4)-375.pdf
spellingShingle R Medicine
Ahmad, S.B.
Cheong, C.S.
Lim, S.Y.
Rahmat, K.
Rozalli, F.I.
Sekaran, S.D.
Sulaiman, H.
Ponnampalavanar, S.
Lim, K.S.
Tan, C.T.
Bilateral thalamic internal medullary lamina involvement in a case of dengue encephalitis
title Bilateral thalamic internal medullary lamina involvement in a case of dengue encephalitis
title_full Bilateral thalamic internal medullary lamina involvement in a case of dengue encephalitis
title_fullStr Bilateral thalamic internal medullary lamina involvement in a case of dengue encephalitis
title_full_unstemmed Bilateral thalamic internal medullary lamina involvement in a case of dengue encephalitis
title_short Bilateral thalamic internal medullary lamina involvement in a case of dengue encephalitis
title_sort bilateral thalamic internal medullary lamina involvement in a case of dengue encephalitis
topic R Medicine
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