Probable impact of age and hypoxia on proliferation and microRNA expression profile of bone marrow-derived human mesenchymal stem cells

Decline in the therapeutic potential of bone marrow-derived mesenchymal stem cells (MSC) is often seen with older donors as compared to young. Although hypoxia is known as an approach to improve the therapeutic potential of MSC in term of cell proliferation and differentiation capacity, its effects...

Full description

Bibliographic Details
Main Authors:	Ali, N.M., Boo, L., Yeap, S.K., Ky, H., Satharasinghe, D.A., Liew, W.C., Ong, H.K., Cheong, S.K., Kamarul, Tunku
Format:	Article
Published:	PeerJ 2016
Subjects:	QH Natural history R Medicine

Similar Items

Probable impact of age and hypoxia on proliferation and microRNA expression profile of bone marrow-derived human mesenchymal stem cells
by: Mohd Ali, Norlaily, et al.
Published: (2016)

Phenotypic and microRNA transcriptomic profiling of the MDA-MB-231 spheroid-enriched CSCs with comparison of MCF-7 microRNA profiling dataset
by: Boo, L., et al.
Published: (2017)

Isolation and characterization of rabbit bone marrow mesenchymal stem cells
by: Tan, S.L., et al.
Published: (2007)

Expansion and preservation of multipotentiality of rabbit bone-marrow derived mesenchymal stem cells in dextran-based microcarrier spin culture
by: Boo, Lily, et al.
Published: (2011)

Human bone marrow-derived Mesenchymal stem cells suppress T cell proliferation by inducing cell cycle arrest
by: Tong, Chih Kong, et al.
Published: (2008)

Chondrogenesis of bone marrow and peripheral blood derived adult human mesenchymal stem cells
by: Mansor, A., et al.
Published: (2008)

Isolation and characterization of rabbit bone marrow-derived mesenchymal stem cells
by: Abofila, Marwan T. M., et al.
Published: (2021)

Isolation, characterization and the multi-lineage differentiation potential of rabbit bone marrow-derived mesenchymal stem cells
by: Tan, S.L., et al.
Published: (2013)

Human peripheral blood derived mesenchymal stem cells demonstrate similar characteristics and chondrogenic differentiation potential to bone marrow derived mesenchymal stem cells
by: Chong, P.P., et al.
Published: (2011)

Hypoxia activated EGFR signaling induces epithelial to mesenchymal transition (EMT)
by: Misra, Ashish, et al.
Published: (2013)

Rapid growth and osteogenic differentiation of mesenchymal stem cells isolated from human bone marrow
by: Shima, Wan nazatul, et al.
Published: (2015)

Tgf-b3 and bfgfinduction of in vitro chondrogenesis in human bone marrow and blood-derived mesenchymal stem cells
by: Chong, P.P., et al.
Published: (2007)

Immunomodulatory effect of Rhaphidophora korthalsii on mice splenocyte, thymocyte and bone marrow cell proliferation and cytokine expression
by: Yeap, Swee Keong, et al.
Published: (2011)

Characterization of bovine-derived porous hydroxyapatite scaffold and its potential to support osteogenic differentiation of human bone marrow derived mesenchymal stem cells
by: Krishnamurithy, G., et al.
Published: (2014)

Evidence of cartilage regeneration by chondrogenic induced bone marrow mesenchymal stem cells in a sheep model.
by: C.C., Ude, et al.
Published: (2011)

Hyaluronic acid with or without bone marrow derived-mesenchymal stem cells improves osteoarthritic knee changes in rat model: a preliminary report
by: Suhaeb, A.M., et al.
Published: (2011)

Potential differentiation of human amniotic epithelial stem and mesenchymal bone marrow cells into cardiomyocytes
by: Motamedi, Batool
Published: (2015)

Isolation And Characterization Of Mesenchymal Cells From Human Bone Marrow And Their Development Into Bone Cells
by: Shahidan, Wan Nazatul Shima
Published: (2007)

Human Wharton's jelly mesenchymal stem cells show unique gene expression compared with bone marrow mesenchymal stem cells using single-cell RNA-sequencing
by: Barrett, Angela N., et al.
Published: (2021)

Uniaxial Cyclic Tensile Stretching at 8% Strain Exclusively Promotes Tenogenic Differentiation of Human Bone Marrow-Derived Mesenchymal Stromal Cells
by: Nam, Hui Yin, et al.
Published: (2019)

Development of a Bayesian Network to Monitor the Probability of Nuclear Proliferation
by: Holcombe, Robert, et al.
Published: (2012)

Development of a Bayesian Network to monitor the probability of nuclear proliferation
by: Holcombe, Robert (Robert Joseph)
Published: (2009)

Hypoxia-induced tumor exosomes promote M2-like macrophage polarization of infiltrating myeloid cells and microRNA-mediated metabolic shift
by: Park, Jung Eun, et al.
Published: (2021)

Expression profile of MicroRNAs in young stroke patients.
by: Tan, K.S., et al.
Published: (2009)

MicroRNAs as biomarkers in stroke pathogenesis
by: Jeyaseelan, K., et al.
Published: (2010)

Bone marrow-derived mesenchymal stem cells modulate BV2 microglia responses to lipopolysaccharide.
by: Ooi, Yin Yin, et al.
Published: (2010)

Discovery of novel anti-inflammatory proteins inspired by bone marrow mesenchymal stem cell secretions
by: Milwid, Jack Miles
Published: (2012)

Pericyte Depletion Results in Hypoxia-Associated Epithelial-to-Mesenchymal Transition and Metastasis Mediated by Met Signaling Pathway
by: Cooke, Vesselina G., et al.
Published: (2014)

Modulatory and regenerative potential of transplanted bone marrow derived mesenchymal stem cells on rifampicin-induced kidney toxicity
by: Danjuma, Lawal, et al.
Published: (2018)

Comparison of In Vitro developmental competence of cloned caprine embryos using donor karyoplasts from adult bone marrow mesenchymal stem cells vs ear fibroblast cells
by: Kwong, P.J., et al.
Published: (2014)

Characterization and expression of senescence marker in prolonged passages of rat bone marrow-derived mesenchymal stem cells
by: Ridzuan, Noridzzaida, et al.
Published: (2016)

Comparative characterization of murine Bone marrow mesenchymal stem cells cultured using two different supplements
by: Lye, Kwan Liang, et al.
Published: (2017)

The role of PTEN in human bone marrow-derived mesenchymal stem cells mediated tumor cells suppression.
by: Toh, Xin Yi.
Published: (2011)

Hypoxia in bone and oxygen releasing biomaterials in fracture treatments using mesenchymal stem cell therapy: a review
by: Teh, Seoh Wei, et al.
Published: (2021)

The multiple facets of mesenchymal stem cells in modulating tumour cells’ proliferation and progression
by: Ramasamy, Rajesh, et al.
Published: (2019)

Effects of strontium ions on the proliferation and mineralization of human fetal mesenchymal stem cells.
by: Lim, Xin Ying.
Published: (2013)

Reciprocal interactions of bone marrow-derived mesenchymal stem cells and BV2 microglia following lipopolysaccharide stimulation
by: Rahmat, Zul'atfi, et al.
Published: (2013)

Comparative evaluation of mouse bone marrow mesenchymal stromal cells characteristics cultured in two different supplemented media
by: Kwan, Liang Lye, et al.
Published: (2022)

Circulatory microRNA-145 expression is increased in cerebral ischemia
by: Gan, C.S., et al.
Published: (2012)

Elucidation of molecular mechanisms under hypoxia and hypoxia / reoxygenation conditions.
by: Chhiti Pandey.
Published: (2011)