Antimicrobial susceptibility of Leptospira spp. isolated from environmental, human and animal sources in Malaysia

Leptospirosis is a zoonosis with worldwide distribution caused by pathogenic spirochetes of the genus Leptospira. The aim of this study was to evaluate the susceptibility of isolates obtained from different hosts. A total of 65 Leptospira isolates from humans (n = 1), zoonoses (rat, n = 60; dog, n =...

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Detalles Bibliográficos
Main Authors: Benacer, D., Mohd Zain, S.N., Ooi, P.T., Thong, Kwai Lin
Formato: Artigo
Idioma:English
Publicado: Medknow Publications 2017
Subjects:
Acceso en liña:http://eprints.um.edu.my/18382/1/Antimicrobial_Susceptibility_of_Leptospira_spp._Isolated_from.pdf
Descripción
Summary:Leptospirosis is a zoonosis with worldwide distribution caused by pathogenic spirochetes of the genus Leptospira. The aim of this study was to evaluate the susceptibility of isolates obtained from different hosts. A total of 65 Leptospira isolates from humans (n = 1), zoonoses (rat, n = 60; dog, n = 1; swine, n = 1) and environment (n = 2) were tested against six antibiotics. All the isolates were resistant to trimethoprim and sulphamethoxazole and had high MIC toward chloramphenicol (MIC90: 6.25 μg/ml). All except one environment isolate were sensitive to ampicillin, doxycycline and penicillin G.