Antimicrobial susceptibility of Leptospira spp. isolated from environmental, human and animal sources in Malaysia
Leptospirosis is a zoonosis with worldwide distribution caused by pathogenic spirochetes of the genus Leptospira. The aim of this study was to evaluate the susceptibility of isolates obtained from different hosts. A total of 65 Leptospira isolates from humans (n = 1), zoonoses (rat, n = 60; dog, n =...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Medknow Publications
2017
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| Online Access: | http://eprints.um.edu.my/18382/1/Antimicrobial_Susceptibility_of_Leptospira_spp._Isolated_from.pdf |
| _version_ | 1825721102934999040 |
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| author | Benacer, D. Mohd Zain, S.N. Ooi, P.T. Thong, Kwai Lin |
| author_facet | Benacer, D. Mohd Zain, S.N. Ooi, P.T. Thong, Kwai Lin |
| author_sort | Benacer, D. |
| collection | UM |
| description | Leptospirosis is a zoonosis with worldwide distribution caused by pathogenic spirochetes of the genus Leptospira. The aim of this study was to evaluate the susceptibility of isolates obtained from different hosts. A total of 65 Leptospira isolates from humans (n = 1), zoonoses (rat, n = 60; dog, n = 1; swine, n = 1) and environment (n = 2) were tested against six antibiotics. All the isolates were resistant to trimethoprim and sulphamethoxazole and had high MIC toward chloramphenicol (MIC90: 6.25 μg/ml). All except one environment isolate were sensitive to ampicillin, doxycycline and penicillin G. |
| first_indexed | 2024-03-06T05:45:15Z |
| format | Article |
| id | um.eprints-18382 |
| institution | Universiti Malaya |
| language | English |
| last_indexed | 2024-03-06T05:45:15Z |
| publishDate | 2017 |
| publisher | Medknow Publications |
| record_format | dspace |
| spelling | um.eprints-183822018-10-15T05:35:38Z http://eprints.um.edu.my/18382/ Antimicrobial susceptibility of Leptospira spp. isolated from environmental, human and animal sources in Malaysia Benacer, D. Mohd Zain, S.N. Ooi, P.T. Thong, Kwai Lin Q Science (General) QH Natural history R Medicine Leptospirosis is a zoonosis with worldwide distribution caused by pathogenic spirochetes of the genus Leptospira. The aim of this study was to evaluate the susceptibility of isolates obtained from different hosts. A total of 65 Leptospira isolates from humans (n = 1), zoonoses (rat, n = 60; dog, n = 1; swine, n = 1) and environment (n = 2) were tested against six antibiotics. All the isolates were resistant to trimethoprim and sulphamethoxazole and had high MIC toward chloramphenicol (MIC90: 6.25 μg/ml). All except one environment isolate were sensitive to ampicillin, doxycycline and penicillin G. Medknow Publications 2017 Article PeerReviewed application/pdf en http://eprints.um.edu.my/18382/1/Antimicrobial_Susceptibility_of_Leptospira_spp._Isolated_from.pdf Benacer, D. and Mohd Zain, S.N. and Ooi, P.T. and Thong, Kwai Lin (2017) Antimicrobial susceptibility of Leptospira spp. isolated from environmental, human and animal sources in Malaysia. Indian Journal of Medical Microbiology, 35 (1). pp. 124-128. ISSN 0255-0857, http://www.ijmm.org/article.asp?issn=0255-0857;year=2017;volume=35;issue=1;spage=124;epage=128;aulast=Benacer |
| spellingShingle | Q Science (General) QH Natural history R Medicine Benacer, D. Mohd Zain, S.N. Ooi, P.T. Thong, Kwai Lin Antimicrobial susceptibility of Leptospira spp. isolated from environmental, human and animal sources in Malaysia |
| title | Antimicrobial susceptibility of Leptospira spp. isolated from environmental, human and animal sources in Malaysia
|
| title_full | Antimicrobial susceptibility of Leptospira spp. isolated from environmental, human and animal sources in Malaysia
|
| title_fullStr | Antimicrobial susceptibility of Leptospira spp. isolated from environmental, human and animal sources in Malaysia
|
| title_full_unstemmed | Antimicrobial susceptibility of Leptospira spp. isolated from environmental, human and animal sources in Malaysia
|
| title_short | Antimicrobial susceptibility of Leptospira spp. isolated from environmental, human and animal sources in Malaysia
|
| title_sort | antimicrobial susceptibility of leptospira spp isolated from environmental human and animal sources in malaysia |
| topic | Q Science (General) QH Natural history R Medicine |
| url | http://eprints.um.edu.my/18382/1/Antimicrobial_Susceptibility_of_Leptospira_spp._Isolated_from.pdf |
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