Novel domino procedures for the synthesis of chromene derivatives and their isomerization

Novel tricyclic keto diesters have been synthesized by a one-pot three-component procedure via DABCO-catalyzed domino Knoevenagel–Michael addition reactions. Also, an efficient four-component reaction for the synthesis of another new group of tricyclic keto diesters has been developed via domino Kno...

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Main Authors: Zonouzi, A., Izakian, Z., Ng, S.W.
Format: Article
Published: Kluwer (now part of Springer) 2016
Subjects:
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author Zonouzi, A.
Izakian, Z.
Ng, S.W.
author_facet Zonouzi, A.
Izakian, Z.
Ng, S.W.
author_sort Zonouzi, A.
collection UM
description Novel tricyclic keto diesters have been synthesized by a one-pot three-component procedure via DABCO-catalyzed domino Knoevenagel–Michael addition reactions. Also, an efficient four-component reaction for the synthesis of another new group of tricyclic keto diesters has been developed via domino Knoevenagel-intramolecular oxo-Diels–Alder reactions. A selective thermal isomerization of the synthesized chromenes to fumarates is also described. X-ray analyses confirm unambiguously the structures of the products.
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spelling um.eprints-186582018-05-14T07:43:06Z http://eprints.um.edu.my/18658/ Novel domino procedures for the synthesis of chromene derivatives and their isomerization Zonouzi, A. Izakian, Z. Ng, S.W. Q Science (General) QD Chemistry Novel tricyclic keto diesters have been synthesized by a one-pot three-component procedure via DABCO-catalyzed domino Knoevenagel–Michael addition reactions. Also, an efficient four-component reaction for the synthesis of another new group of tricyclic keto diesters has been developed via domino Knoevenagel-intramolecular oxo-Diels–Alder reactions. A selective thermal isomerization of the synthesized chromenes to fumarates is also described. X-ray analyses confirm unambiguously the structures of the products. Kluwer (now part of Springer) 2016 Article PeerReviewed Zonouzi, A. and Izakian, Z. and Ng, S.W. (2016) Novel domino procedures for the synthesis of chromene derivatives and their isomerization. Molecular Diversity, 20 (3). pp. 627-638. ISSN 1381-1991, DOI https://doi.org/10.1007/s11030-016-9664-0 <https://doi.org/10.1007/s11030-016-9664-0>. https://doi.org/10.1007/s11030-016-9664-0 doi:10.1007/s11030-016-9664-0
spellingShingle Q Science (General)
QD Chemistry
Zonouzi, A.
Izakian, Z.
Ng, S.W.
Novel domino procedures for the synthesis of chromene derivatives and their isomerization
title Novel domino procedures for the synthesis of chromene derivatives and their isomerization
title_full Novel domino procedures for the synthesis of chromene derivatives and their isomerization
title_fullStr Novel domino procedures for the synthesis of chromene derivatives and their isomerization
title_full_unstemmed Novel domino procedures for the synthesis of chromene derivatives and their isomerization
title_short Novel domino procedures for the synthesis of chromene derivatives and their isomerization
title_sort novel domino procedures for the synthesis of chromene derivatives and their isomerization
topic Q Science (General)
QD Chemistry
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AT izakianz noveldominoproceduresforthesynthesisofchromenederivativesandtheirisomerization
AT ngsw noveldominoproceduresforthesynthesisofchromenederivativesandtheirisomerization