Complete mitochondrial genome of Angiostrongylus malaysiensis lungworm and molecular phylogeny of Metastrongyloid nematodes
Angiostrongylus malaysiensis is a nematode parasite of various rat species. When first documented in Malaysia, it was referred to as A. cantonensis. Unlike A. cantonensis, the complete mitochondrial genome of A. malaysiensis has not been documented. We report here its complete mitogenome, its differ...
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Elsevier
2016
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| author | Yong, Hoi Sen Song, Sze Looi Eamsobhana, Praphathip Lim, Phaik Eem |
| author_facet | Yong, Hoi Sen Song, Sze Looi Eamsobhana, Praphathip Lim, Phaik Eem |
| author_sort | Yong, Hoi Sen |
| collection | UM |
| description | Angiostrongylus malaysiensis is a nematode parasite of various rat species. When first documented in Malaysia, it was referred to as A. cantonensis. Unlike A. cantonensis, the complete mitochondrial genome of A. malaysiensis has not been documented. We report here its complete mitogenome, its differentiation from A. cantonensis, and the phylogenetic relationships with its congeners and other Metastrongyloid taxa. The whole mitogenome of A. malaysiensis had a total length of 13,516 bp, comprising 36 genes (12 PCGs, 2 rRNA and 22 tRNA genes) and a control region. It is longer than that of A. cantonensis (13,509 bp). Its control region had a long poly T-stretch of 12 bp which was not present in A. cantonensis. A. malaysiensis and A. cantonensis had identical start codon for the 12 PCGs, but four PCGs (atp6, cob, nad2, nad6) had different stop codon. The cloverleaf structure for the 22 tRNAs was similar in A. malaysiensis and A. cantonensis except the TΨC-arm was absent in trnV for A. malaysiensis but present in A. cantonensis. The Angiostrongylus genus was monophyletic, with A. malaysiensis and A. cantonensis forming a distinct lineage from that of A. costaricensis and A. vasorum. The genetic distance between A. malaysiensis and A. cantonensis was p = 11.9% based on 12 PCGs, p = 9.5% based on 2 rRNA genes, and p = 11.6% based on 14 mt-genes. The mitogenome will prove useful for studies on phylogenetics and systematics of Angiostrongylus lungworms and other Metastrongyloid nematodes. |
| first_indexed | 2024-03-06T05:46:17Z |
| format | Article |
| id | um.eprints-18766 |
| institution | Universiti Malaya |
| last_indexed | 2024-03-06T05:46:17Z |
| publishDate | 2016 |
| publisher | Elsevier |
| record_format | dspace |
| spelling | um.eprints-187662019-12-04T08:43:40Z http://eprints.um.edu.my/18766/ Complete mitochondrial genome of Angiostrongylus malaysiensis lungworm and molecular phylogeny of Metastrongyloid nematodes Yong, Hoi Sen Song, Sze Looi Eamsobhana, Praphathip Lim, Phaik Eem Q Science (General) QH Natural history Angiostrongylus malaysiensis is a nematode parasite of various rat species. When first documented in Malaysia, it was referred to as A. cantonensis. Unlike A. cantonensis, the complete mitochondrial genome of A. malaysiensis has not been documented. We report here its complete mitogenome, its differentiation from A. cantonensis, and the phylogenetic relationships with its congeners and other Metastrongyloid taxa. The whole mitogenome of A. malaysiensis had a total length of 13,516 bp, comprising 36 genes (12 PCGs, 2 rRNA and 22 tRNA genes) and a control region. It is longer than that of A. cantonensis (13,509 bp). Its control region had a long poly T-stretch of 12 bp which was not present in A. cantonensis. A. malaysiensis and A. cantonensis had identical start codon for the 12 PCGs, but four PCGs (atp6, cob, nad2, nad6) had different stop codon. The cloverleaf structure for the 22 tRNAs was similar in A. malaysiensis and A. cantonensis except the TΨC-arm was absent in trnV for A. malaysiensis but present in A. cantonensis. The Angiostrongylus genus was monophyletic, with A. malaysiensis and A. cantonensis forming a distinct lineage from that of A. costaricensis and A. vasorum. The genetic distance between A. malaysiensis and A. cantonensis was p = 11.9% based on 12 PCGs, p = 9.5% based on 2 rRNA genes, and p = 11.6% based on 14 mt-genes. The mitogenome will prove useful for studies on phylogenetics and systematics of Angiostrongylus lungworms and other Metastrongyloid nematodes. Elsevier 2016 Article PeerReviewed Yong, Hoi Sen and Song, Sze Looi and Eamsobhana, Praphathip and Lim, Phaik Eem (2016) Complete mitochondrial genome of Angiostrongylus malaysiensis lungworm and molecular phylogeny of Metastrongyloid nematodes. Acta Tropica, 161. pp. 33-40. ISSN 0001-706X, DOI https://doi.org/10.1016/j.actatropica.2016.05.002 <https://doi.org/10.1016/j.actatropica.2016.05.002>. http://dx.doi.org/10.1016/j.actatropica.2016.05.002 doi:10.1016/j.actatropica.2016.05.002 |
| spellingShingle | Q Science (General) QH Natural history Yong, Hoi Sen Song, Sze Looi Eamsobhana, Praphathip Lim, Phaik Eem Complete mitochondrial genome of Angiostrongylus malaysiensis lungworm and molecular phylogeny of Metastrongyloid nematodes |
| title | Complete mitochondrial genome of Angiostrongylus malaysiensis lungworm and molecular phylogeny of Metastrongyloid nematodes |
| title_full | Complete mitochondrial genome of Angiostrongylus malaysiensis lungworm and molecular phylogeny of Metastrongyloid nematodes |
| title_fullStr | Complete mitochondrial genome of Angiostrongylus malaysiensis lungworm and molecular phylogeny of Metastrongyloid nematodes |
| title_full_unstemmed | Complete mitochondrial genome of Angiostrongylus malaysiensis lungworm and molecular phylogeny of Metastrongyloid nematodes |
| title_short | Complete mitochondrial genome of Angiostrongylus malaysiensis lungworm and molecular phylogeny of Metastrongyloid nematodes |
| title_sort | complete mitochondrial genome of angiostrongylus malaysiensis lungworm and molecular phylogeny of metastrongyloid nematodes |
| topic | Q Science (General) QH Natural history |
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