Tailoring the morphological features of hydrothermally synthesized mesoporous hydroxyapatite using polyphenols and phosphate sources
Hydroxyapatite (HA) is a well-known material for biomedical applications and its performance depends greatly on its morphological features. Therefore, preparation of mesoporous HA with high surface area and adsorption capacity is highly deserved. In this research, a hydrothermal approach to synthesi...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Published: |
Elsevier
2017
|
| Subjects: |
| _version_ | 1825721178032963584 |
|---|---|
| author | Zhou, H. Yang, M. Hou, S. Ni, X. Bi, Y. Wang, W. Kutty, M.G. Yang, L. |
| author_facet | Zhou, H. Yang, M. Hou, S. Ni, X. Bi, Y. Wang, W. Kutty, M.G. Yang, L. |
| author_sort | Zhou, H. |
| collection | UM |
| description | Hydroxyapatite (HA) is a well-known material for biomedical applications and its performance depends greatly on its morphological features. Therefore, preparation of mesoporous HA with high surface area and adsorption capacity is highly deserved. In this research, a hydrothermal approach to synthesize mesoporous HA without post-processing calcination step is presented. The possibility using different polyphenols to generate mesoporous HA as well as using different phosphate sources to tailor the morphological features of HA is investigated. The as-prepared mesoporous HA particles are characterized by XRD, FTIR, SEM, TEM, BET, and zeta potential. Besides, the impacts of HA morphological features on model drug Dox are also studied. It is expected the strong interaction between –OH of polyphenols and Ca2+ makes polyphenols molecules occupy the inner sites of growing HA particles. After the removal of polyphenols by hydrothermal treatment and ethanol extraction, the occupied sites are transformed into mesopores. The typical mesoporous HA generated in present work has a rod-like morphology with BET specific surface area of 106.6 m2/g and an average pore size of 14.4 nm. |
| first_indexed | 2024-03-06T05:46:25Z |
| format | Article |
| id | um.eprints-18810 |
| institution | Universiti Malaya |
| last_indexed | 2024-03-06T05:46:25Z |
| publishDate | 2017 |
| publisher | Elsevier |
| record_format | dspace |
| spelling | um.eprints-188102018-06-06T05:47:32Z http://eprints.um.edu.my/18810/ Tailoring the morphological features of hydrothermally synthesized mesoporous hydroxyapatite using polyphenols and phosphate sources Zhou, H. Yang, M. Hou, S. Ni, X. Bi, Y. Wang, W. Kutty, M.G. Yang, L. R Medicine RK Dentistry TA Engineering (General). Civil engineering (General) Hydroxyapatite (HA) is a well-known material for biomedical applications and its performance depends greatly on its morphological features. Therefore, preparation of mesoporous HA with high surface area and adsorption capacity is highly deserved. In this research, a hydrothermal approach to synthesize mesoporous HA without post-processing calcination step is presented. The possibility using different polyphenols to generate mesoporous HA as well as using different phosphate sources to tailor the morphological features of HA is investigated. The as-prepared mesoporous HA particles are characterized by XRD, FTIR, SEM, TEM, BET, and zeta potential. Besides, the impacts of HA morphological features on model drug Dox are also studied. It is expected the strong interaction between –OH of polyphenols and Ca2+ makes polyphenols molecules occupy the inner sites of growing HA particles. After the removal of polyphenols by hydrothermal treatment and ethanol extraction, the occupied sites are transformed into mesopores. The typical mesoporous HA generated in present work has a rod-like morphology with BET specific surface area of 106.6 m2/g and an average pore size of 14.4 nm. Elsevier 2017 Article PeerReviewed Zhou, H. and Yang, M. and Hou, S. and Ni, X. and Bi, Y. and Wang, W. and Kutty, M.G. and Yang, L. (2017) Tailoring the morphological features of hydrothermally synthesized mesoporous hydroxyapatite using polyphenols and phosphate sources. Ceramics International, 43 (15). pp. 12851-12856. ISSN 0272-8842, DOI https://doi.org/10.1016/j.ceramint.2017.06.176 <https://doi.org/10.1016/j.ceramint.2017.06.176>. http://dx.doi.org/10.1016/j.ceramint.2017.06.176 doi:10.1016/j.ceramint.2017.06.176 |
| spellingShingle | R Medicine RK Dentistry TA Engineering (General). Civil engineering (General) Zhou, H. Yang, M. Hou, S. Ni, X. Bi, Y. Wang, W. Kutty, M.G. Yang, L. Tailoring the morphological features of hydrothermally synthesized mesoporous hydroxyapatite using polyphenols and phosphate sources |
| title | Tailoring the morphological features of hydrothermally synthesized mesoporous hydroxyapatite using polyphenols and phosphate sources |
| title_full | Tailoring the morphological features of hydrothermally synthesized mesoporous hydroxyapatite using polyphenols and phosphate sources |
| title_fullStr | Tailoring the morphological features of hydrothermally synthesized mesoporous hydroxyapatite using polyphenols and phosphate sources |
| title_full_unstemmed | Tailoring the morphological features of hydrothermally synthesized mesoporous hydroxyapatite using polyphenols and phosphate sources |
| title_short | Tailoring the morphological features of hydrothermally synthesized mesoporous hydroxyapatite using polyphenols and phosphate sources |
| title_sort | tailoring the morphological features of hydrothermally synthesized mesoporous hydroxyapatite using polyphenols and phosphate sources |
| topic | R Medicine RK Dentistry TA Engineering (General). Civil engineering (General) |
| work_keys_str_mv | AT zhouh tailoringthemorphologicalfeaturesofhydrothermallysynthesizedmesoporoushydroxyapatiteusingpolyphenolsandphosphatesources AT yangm tailoringthemorphologicalfeaturesofhydrothermallysynthesizedmesoporoushydroxyapatiteusingpolyphenolsandphosphatesources AT hous tailoringthemorphologicalfeaturesofhydrothermallysynthesizedmesoporoushydroxyapatiteusingpolyphenolsandphosphatesources AT nix tailoringthemorphologicalfeaturesofhydrothermallysynthesizedmesoporoushydroxyapatiteusingpolyphenolsandphosphatesources AT biy tailoringthemorphologicalfeaturesofhydrothermallysynthesizedmesoporoushydroxyapatiteusingpolyphenolsandphosphatesources AT wangw tailoringthemorphologicalfeaturesofhydrothermallysynthesizedmesoporoushydroxyapatiteusingpolyphenolsandphosphatesources AT kuttymg tailoringthemorphologicalfeaturesofhydrothermallysynthesizedmesoporoushydroxyapatiteusingpolyphenolsandphosphatesources AT yangl tailoringthemorphologicalfeaturesofhydrothermallysynthesizedmesoporoushydroxyapatiteusingpolyphenolsandphosphatesources |