Development of poly (1, 8-octanediol citrate)/chitosan blend films for tissue engineering applications
Blends of poly (1, 8-octanediol citrate) (POC) and chitosan (CS) were prepared through solution casting technique. Films with different component fractions (POC/CS: 100/0, 90/10, 80/20, 70/30, 60/40, and 0/100) were successfully prepared and characterized for their mechanical, thermal, structural an...
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| Format: | Article |
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Elsevier
2017
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| author | Zeimaran, Ehsan Pourshahrestani, Sara Pingguan-Murphy, Belinda Kong, Daniel Naveen, Sangeetha Vasudevaraj Kamarul, Tunku Kadri, Nahrizul Adib |
| author_facet | Zeimaran, Ehsan Pourshahrestani, Sara Pingguan-Murphy, Belinda Kong, Daniel Naveen, Sangeetha Vasudevaraj Kamarul, Tunku Kadri, Nahrizul Adib |
| author_sort | Zeimaran, Ehsan |
| collection | UM |
| description | Blends of poly (1, 8-octanediol citrate) (POC) and chitosan (CS) were prepared through solution casting technique. Films with different component fractions (POC/CS: 100/0, 90/10, 80/20, 70/30, 60/40, and 0/100) were successfully prepared and characterized for their mechanical, thermal, structural and morphological properties as well as biocompatibility. The incorporation of CS to POC significantly increased tensile strength and elastic modulus and presented limited influences on pH variation which is important to the biocompatibility of biomaterial implants. The assessment of surface topography indicated that blending could enhance and control the surface roughness of the pure films. POC/CS blends well-supported human dermal fibroblast cells attachment and proliferation, and thus can be used for a range of tissue engineering applications. |
| first_indexed | 2024-03-06T05:46:28Z |
| format | Article |
| id | um.eprints-18827 |
| institution | Universiti Malaya |
| last_indexed | 2024-03-06T05:46:28Z |
| publishDate | 2017 |
| publisher | Elsevier |
| record_format | dspace |
| spelling | um.eprints-188272021-01-20T08:30:08Z http://eprints.um.edu.my/18827/ Development of poly (1, 8-octanediol citrate)/chitosan blend films for tissue engineering applications Zeimaran, Ehsan Pourshahrestani, Sara Pingguan-Murphy, Belinda Kong, Daniel Naveen, Sangeetha Vasudevaraj Kamarul, Tunku Kadri, Nahrizul Adib R Medicine TA Engineering (General). Civil engineering (General) Blends of poly (1, 8-octanediol citrate) (POC) and chitosan (CS) were prepared through solution casting technique. Films with different component fractions (POC/CS: 100/0, 90/10, 80/20, 70/30, 60/40, and 0/100) were successfully prepared and characterized for their mechanical, thermal, structural and morphological properties as well as biocompatibility. The incorporation of CS to POC significantly increased tensile strength and elastic modulus and presented limited influences on pH variation which is important to the biocompatibility of biomaterial implants. The assessment of surface topography indicated that blending could enhance and control the surface roughness of the pure films. POC/CS blends well-supported human dermal fibroblast cells attachment and proliferation, and thus can be used for a range of tissue engineering applications. Elsevier 2017 Article PeerReviewed Zeimaran, Ehsan and Pourshahrestani, Sara and Pingguan-Murphy, Belinda and Kong, Daniel and Naveen, Sangeetha Vasudevaraj and Kamarul, Tunku and Kadri, Nahrizul Adib (2017) Development of poly (1, 8-octanediol citrate)/chitosan blend films for tissue engineering applications. Carbohydrate Polymers, 175. pp. 618-627. ISSN 0144-8617, DOI https://doi.org/10.1016/j.carbpol.2017.08.038 <https://doi.org/10.1016/j.carbpol.2017.08.038>. http://dx.doi.org/10.1016/j.carbpol.2017.08.038 doi:10.1016/j.carbpol.2017.08.038 |
| spellingShingle | R Medicine TA Engineering (General). Civil engineering (General) Zeimaran, Ehsan Pourshahrestani, Sara Pingguan-Murphy, Belinda Kong, Daniel Naveen, Sangeetha Vasudevaraj Kamarul, Tunku Kadri, Nahrizul Adib Development of poly (1, 8-octanediol citrate)/chitosan blend films for tissue engineering applications |
| title | Development of poly (1, 8-octanediol citrate)/chitosan blend films for tissue engineering applications |
| title_full | Development of poly (1, 8-octanediol citrate)/chitosan blend films for tissue engineering applications |
| title_fullStr | Development of poly (1, 8-octanediol citrate)/chitosan blend films for tissue engineering applications |
| title_full_unstemmed | Development of poly (1, 8-octanediol citrate)/chitosan blend films for tissue engineering applications |
| title_short | Development of poly (1, 8-octanediol citrate)/chitosan blend films for tissue engineering applications |
| title_sort | development of poly 1 8 octanediol citrate chitosan blend films for tissue engineering applications |
| topic | R Medicine TA Engineering (General). Civil engineering (General) |
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