Linear-regression convolutional neural network for fully automated coronary lumen segmentation in intravascular optical coherence tomography

Intravascular optical coherence tomography (OCT) is an optical imaging modality commonly used in the assessment of coronary artery diseases during percutaneous coronary intervention. Manual segmentation to assess luminal stenosis from OCT pullback scans is challenging and time consuming. We propose...

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Main Authors: Yong, Y.L., Tan, L.K., McLaughlin, R.A., Chee, K.H., Liew, Y.M.
Format: Article
Published: International Society for Optical Engineering (SPIE) 2017
Subjects:
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author Yong, Y.L.
Tan, L.K.
McLaughlin, R.A.
Chee, K.H.
Liew, Y.M.
author_facet Yong, Y.L.
Tan, L.K.
McLaughlin, R.A.
Chee, K.H.
Liew, Y.M.
author_sort Yong, Y.L.
collection UM
description Intravascular optical coherence tomography (OCT) is an optical imaging modality commonly used in the assessment of coronary artery diseases during percutaneous coronary intervention. Manual segmentation to assess luminal stenosis from OCT pullback scans is challenging and time consuming. We propose a linear-regression convolutional neural network to automatically perform vessel lumen segmentation, parameterized in terms of radial distances from the catheter centroid in polar space. Benchmarked against gold-standard manual segmentation, our proposed algorithm achieves average locational accuracy of the vessel wall of 22 microns, and 0.985 and 0.970 in Dice coefficient and Jaccard similarity index, respectively. The average absolute error of luminal area estimation is 1.38%. The processing rate is 40.6 ms per image, suggesting the potential to be incorporated into a clinical workflow and to provide quantitative assessment of vessel lumen in an intraoperative time frame.
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spelling um.eprints-188972018-06-28T06:46:10Z http://eprints.um.edu.my/18897/ Linear-regression convolutional neural network for fully automated coronary lumen segmentation in intravascular optical coherence tomography Yong, Y.L. Tan, L.K. McLaughlin, R.A. Chee, K.H. Liew, Y.M. R Medicine T Technology (General) Intravascular optical coherence tomography (OCT) is an optical imaging modality commonly used in the assessment of coronary artery diseases during percutaneous coronary intervention. Manual segmentation to assess luminal stenosis from OCT pullback scans is challenging and time consuming. We propose a linear-regression convolutional neural network to automatically perform vessel lumen segmentation, parameterized in terms of radial distances from the catheter centroid in polar space. Benchmarked against gold-standard manual segmentation, our proposed algorithm achieves average locational accuracy of the vessel wall of 22 microns, and 0.985 and 0.970 in Dice coefficient and Jaccard similarity index, respectively. The average absolute error of luminal area estimation is 1.38%. The processing rate is 40.6 ms per image, suggesting the potential to be incorporated into a clinical workflow and to provide quantitative assessment of vessel lumen in an intraoperative time frame. International Society for Optical Engineering (SPIE) 2017 Article PeerReviewed Yong, Y.L. and Tan, L.K. and McLaughlin, R.A. and Chee, K.H. and Liew, Y.M. (2017) Linear-regression convolutional neural network for fully automated coronary lumen segmentation in intravascular optical coherence tomography. Journal of Biomedical Optics (JBO), 22 (12). p. 1. DOI https://doi.org/10.1117/1.JBO.22.12.126005 <https://doi.org/10.1117/1.JBO.22.12.126005>. http://dx.doi.org/10.1117/1.JBO.22.12.126005 doi:10.1117/1.JBO.22.12.126005
spellingShingle R Medicine
T Technology (General)
Yong, Y.L.
Tan, L.K.
McLaughlin, R.A.
Chee, K.H.
Liew, Y.M.
Linear-regression convolutional neural network for fully automated coronary lumen segmentation in intravascular optical coherence tomography
title Linear-regression convolutional neural network for fully automated coronary lumen segmentation in intravascular optical coherence tomography
title_full Linear-regression convolutional neural network for fully automated coronary lumen segmentation in intravascular optical coherence tomography
title_fullStr Linear-regression convolutional neural network for fully automated coronary lumen segmentation in intravascular optical coherence tomography
title_full_unstemmed Linear-regression convolutional neural network for fully automated coronary lumen segmentation in intravascular optical coherence tomography
title_short Linear-regression convolutional neural network for fully automated coronary lumen segmentation in intravascular optical coherence tomography
title_sort linear regression convolutional neural network for fully automated coronary lumen segmentation in intravascular optical coherence tomography
topic R Medicine
T Technology (General)
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