VP1 residues around the five-fold axis of enterovirus A71 mediate heparan sulfate interaction
Enterovirus A71 (EV-A71) is a neurotropic enterovirus that uses heparan sulfate as an attachment receptor. The molecular determinants of EV-A71-heparan sulfate interaction are unknown. With In silico heparin docking and mutagenesis of all possible lysine residues in VP1, we identified that K162, K24...
| Huvudupphovsmän: | , , , , |
|---|---|
| Materialtyp: | Artikel |
| Publicerad: |
Elsevier
2017
|
| Ämnen: |