Copy number variation in exportin-4 (XPO4) gene and its association with histological severity of non-alcoholic fatty liver disease

A recent genome-wide copy number (CNV) scan identified a 13q12.11 duplication in the exportin-4 (XPO4) gene to be associated with non-alcoholic steatohepatitis (NASH). We sought to confirm the finding in a larger cohort and to assess the serum XPO4 pattern in a broad spectrum of non-alcoholic fatty...

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Principais autores: Zain, Shamsul Mohd, Mohamed, Zahurin, Pirmohamed, M., Tan, H.L., Alshawsh, Mohammed Abdullah, Mahadeva, Sanjiv, Chan, Wah Kheong, Mustapha, N.R.N., Mohamed, Rosmawati
Formato: Artigo
Publicado em: Nature Publishing Group 2015
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