Synthesis, characterization and apoptotic activity of quinazolinone Schiff base derivatives toward MCF-7 cells via intrinsic and extrinsic apoptosis pathways

Synthesis, characterization and apoptotic activity of quinazolinone Schiff base derivatives toward MCF-7 cells via intrinsic and extrinsic apoptosis pathways

The current study investigated the cytotoxic effect of 3-(5-chloro-2-hydroxybenzylideneamino)-2-(5-chloro-2-hydroxyphenyl)-2,3-dihydroquinazolin-41(H)-one (A) and 3-(5-nitro-2-hydroxybenzylideneamino)-2-(5-nitro-2-hydroxyphenyl)-2,3-dihydroquinazolin-4(1H)-one (B) on MCF-7, MDA-MB-231, MCF-10A and W...

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Detalhes bibliográficos
Principais autores: Zahedifard, M., Faraj, F.L., Paydar, M., Looi, C.Y., Hajrezaei, M., Hasanpourghadi, M., Kamalidehghan, B., Majid, N.A., Ali, H.M., Abdulla, M.A.
Formato: Artigo
Publicado em: Nature Publishing Group 2015
Assuntos:
Q Science (General)
R Medicine

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