DNA Interactions and Cytotoxicity of the Aryls-Vertexed Zinc(II) Thiosemicarbazone Complex
A new mononuclear zinc complex of N-phenyl-substituted thiophene thiosemicarbazone ligand [Zn(Httsc-N-Ph)2] was synthesized and characterized, and investigated as nuclease mimic. As compared to carboplatin, a much greater activity against HeLa cells is exhibited by [Zn(Httsc-N-Ph)2] which binds to D...
| Principais autores: | , , , |
|---|---|
| Formato: | Artigo |
| Publicado em: |
Chemical Society of Japan
2015
|
| Assuntos: |