Basaloid squamous cell carcinoma of the sinonasal tract with metastasis to the liver: A case report and literature review

Basaloid squamous cell carcinoma (BSCC) is a rare subtype of squamous cell carcinoma. To date, only 95 cases of sinonasal BSCC have been reported in the English-language literature, and they account for 5% of all cases of head and neck BSCC. We describe what we believe is only the second reported ca...

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Main Authors: Toe, B.P., Ramli, Norlisah, Lam, S.Y., Wong, Kum Thong, Prepageran, Narayanan
Format: Article
Published: SAGE Publications 2015
Subjects:
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author Toe, B.P.
Ramli, Norlisah
Lam, S.Y.
Wong, Kum Thong
Prepageran, Narayanan
author_facet Toe, B.P.
Ramli, Norlisah
Lam, S.Y.
Wong, Kum Thong
Prepageran, Narayanan
author_sort Toe, B.P.
collection UM
description Basaloid squamous cell carcinoma (BSCC) is a rare subtype of squamous cell carcinoma. To date, only 95 cases of sinonasal BSCC have been reported in the English-language literature, and they account for 5% of all cases of head and neck BSCC. We describe what we believe is only the second reported case of a sinonasal tract BSCC that metastasized to the liver. The patient was a 36-year-old woman who presented with right-sided nasal obstruction and a foul-smelling discharge. Clinical examination and imaging identified a large lobulated enhancing mass in the right nasal cavity. Following excision of the mass, the patient was scheduled for radiotherapy. However, before it could be administered, follow-up imaging detected a metastasis to the liver and lung, and the patient was switched to chemotherapy. Initially, she responded well clinically, but at 5 months postoperatively, a follow-up CT showed an increasing metastatic presence in the liver and bone. The patient died of her disease 1 year after surgery.
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spelling um.eprints-195362020-02-12T04:04:53Z http://eprints.um.edu.my/19536/ Basaloid squamous cell carcinoma of the sinonasal tract with metastasis to the liver: A case report and literature review Toe, B.P. Ramli, Norlisah Lam, S.Y. Wong, Kum Thong Prepageran, Narayanan R Medicine Basaloid squamous cell carcinoma (BSCC) is a rare subtype of squamous cell carcinoma. To date, only 95 cases of sinonasal BSCC have been reported in the English-language literature, and they account for 5% of all cases of head and neck BSCC. We describe what we believe is only the second reported case of a sinonasal tract BSCC that metastasized to the liver. The patient was a 36-year-old woman who presented with right-sided nasal obstruction and a foul-smelling discharge. Clinical examination and imaging identified a large lobulated enhancing mass in the right nasal cavity. Following excision of the mass, the patient was scheduled for radiotherapy. However, before it could be administered, follow-up imaging detected a metastasis to the liver and lung, and the patient was switched to chemotherapy. Initially, she responded well clinically, but at 5 months postoperatively, a follow-up CT showed an increasing metastatic presence in the liver and bone. The patient died of her disease 1 year after surgery. SAGE Publications 2015 Article PeerReviewed Toe, B.P. and Ramli, Norlisah and Lam, S.Y. and Wong, Kum Thong and Prepageran, Narayanan (2015) Basaloid squamous cell carcinoma of the sinonasal tract with metastasis to the liver: A case report and literature review. Ear, Nose & Throat Journal, 94 (2). E27. ISSN 0145-5613, https://www.entjournal.com/article/basaloid-squamous-cell-carcinoma-sinonasal-tract-metastasis-liver-case-report-and-literature
spellingShingle R Medicine
Toe, B.P.
Ramli, Norlisah
Lam, S.Y.
Wong, Kum Thong
Prepageran, Narayanan
Basaloid squamous cell carcinoma of the sinonasal tract with metastasis to the liver: A case report and literature review
title Basaloid squamous cell carcinoma of the sinonasal tract with metastasis to the liver: A case report and literature review
title_full Basaloid squamous cell carcinoma of the sinonasal tract with metastasis to the liver: A case report and literature review
title_fullStr Basaloid squamous cell carcinoma of the sinonasal tract with metastasis to the liver: A case report and literature review
title_full_unstemmed Basaloid squamous cell carcinoma of the sinonasal tract with metastasis to the liver: A case report and literature review
title_short Basaloid squamous cell carcinoma of the sinonasal tract with metastasis to the liver: A case report and literature review
title_sort basaloid squamous cell carcinoma of the sinonasal tract with metastasis to the liver a case report and literature review
topic R Medicine
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