Faecal prevalence of extended-spectrum ß-lactamase (ESBL)-producing coliforms in a geriatric population and among haematology patients
Antimicrobial resistance to the extended-spectrum cephalosporins is increasingly reported worldwide. In the local setting, nosocomial infections with multi-resistant Gram-negative bacilli are not uncommon and are a growing concern. However, there is limited data on the carriage rates of such organis...
| Những tác giả chính: | , , , , , , , |
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| Định dạng: | Bài viết |
| Ngôn ngữ: | English |
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Malaysian Society of Pathologists
2005
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| Những chủ đề: | |
| Truy cập trực tuyến: | http://eprints.um.edu.my/1960/1/1.pdf |
| _version_ | 1825718599552073728 |
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| author | Nurul Atifah, M.A. Loo, H.K.C. Wong, E.H. Subramaniam, G. Ho, S.E. Selvi, P. Parasakthi, N. Kamarulzaman, A. |
| author_facet | Nurul Atifah, M.A. Loo, H.K.C. Wong, E.H. Subramaniam, G. Ho, S.E. Selvi, P. Parasakthi, N. Kamarulzaman, A. |
| author_sort | Nurul Atifah, M.A. |
| collection | UM |
| description | Antimicrobial resistance to the extended-spectrum cephalosporins is increasingly reported worldwide. In the local setting, nosocomial infections with multi-resistant Gram-negative bacilli are not uncommon and are a growing concern. However, there is limited data on the carriage rates of such organisms in the local setting. In May 2001, a prospective study was carried out to determine the enteric carriage rates of ceftazidime-resistant Gram negative bacilli (CAZ-R GNB) among residents of nursing homes and from in-patients of the geriatric and adult haematology wards of University Malaya Medical Centre. Ceftazidime-resistant Gram-negative bacilli (CAZ-R GNB) were detected in 25 samples (30%), out of which 6 were from nursing home residents, 5 from geriatric in-patients and 14 from the haematology unit. A total of 28 CAZ-R GNB were isolated and Escherichia coli (10) and Klebsiella pneumoniae (7) were the predominant organisms. Resistance to ceftazidime in E. coli and Klebsiella was mediated by extended-spectrum beta-lactamases (ESBLs). Although the majority of the CAZ-R GNB were from patients in the haematology ward, the six nursing home residents with CAZ-R GNB were enteric carriers of ESBL-producing coliforms. Prior exposure to antibiotics was associated with carriage of ESBL organisms and to a lesser extent, the presence of urinary catheters. |
| first_indexed | 2024-03-06T05:06:53Z |
| format | Article |
| id | um.eprints-1960 |
| institution | Universiti Malaya |
| language | English |
| last_indexed | 2024-03-06T05:06:53Z |
| publishDate | 2005 |
| publisher | Malaysian Society of Pathologists |
| record_format | dspace |
| spelling | um.eprints-19602014-10-20T04:05:53Z http://eprints.um.edu.my/1960/ Faecal prevalence of extended-spectrum ß-lactamase (ESBL)-producing coliforms in a geriatric population and among haematology patients Nurul Atifah, M.A. Loo, H.K.C. Wong, E.H. Subramaniam, G. Ho, S.E. Selvi, P. Parasakthi, N. Kamarulzaman, A. R Medicine Antimicrobial resistance to the extended-spectrum cephalosporins is increasingly reported worldwide. In the local setting, nosocomial infections with multi-resistant Gram-negative bacilli are not uncommon and are a growing concern. However, there is limited data on the carriage rates of such organisms in the local setting. In May 2001, a prospective study was carried out to determine the enteric carriage rates of ceftazidime-resistant Gram negative bacilli (CAZ-R GNB) among residents of nursing homes and from in-patients of the geriatric and adult haematology wards of University Malaya Medical Centre. Ceftazidime-resistant Gram-negative bacilli (CAZ-R GNB) were detected in 25 samples (30%), out of which 6 were from nursing home residents, 5 from geriatric in-patients and 14 from the haematology unit. A total of 28 CAZ-R GNB were isolated and Escherichia coli (10) and Klebsiella pneumoniae (7) were the predominant organisms. Resistance to ceftazidime in E. coli and Klebsiella was mediated by extended-spectrum beta-lactamases (ESBLs). Although the majority of the CAZ-R GNB were from patients in the haematology ward, the six nursing home residents with CAZ-R GNB were enteric carriers of ESBL-producing coliforms. Prior exposure to antibiotics was associated with carriage of ESBL organisms and to a lesser extent, the presence of urinary catheters. Malaysian Society of Pathologists 2005 Article PeerReviewed application/pdf en http://eprints.um.edu.my/1960/1/1.pdf Nurul Atifah, M.A. and Loo, H.K.C. and Wong, E.H. and Subramaniam, G. and Ho, S.E. and Selvi, P. and Parasakthi, N. and Kamarulzaman, A. (2005) Faecal prevalence of extended-spectrum ß-lactamase (ESBL)-producing coliforms in a geriatric population and among haematology patients. Malaysian Journal of Pathology, 27 (2). pp. 75-81. ISSN 0126-8635, DOI http://myais.fsktm.um.edu.my/1806/1/01Faecal.pdf. http://myais.fsktm.um.edu.my/1806/ http://myais.fsktm.um.edu.my/1806/1/01Faecal.pdf |
| spellingShingle | R Medicine Nurul Atifah, M.A. Loo, H.K.C. Wong, E.H. Subramaniam, G. Ho, S.E. Selvi, P. Parasakthi, N. Kamarulzaman, A. Faecal prevalence of extended-spectrum ß-lactamase (ESBL)-producing coliforms in a geriatric population and among haematology patients |
| title | Faecal prevalence of extended-spectrum ß-lactamase (ESBL)-producing coliforms in a geriatric population and among haematology patients |
| title_full | Faecal prevalence of extended-spectrum ß-lactamase (ESBL)-producing coliforms in a geriatric population and among haematology patients |
| title_fullStr | Faecal prevalence of extended-spectrum ß-lactamase (ESBL)-producing coliforms in a geriatric population and among haematology patients |
| title_full_unstemmed | Faecal prevalence of extended-spectrum ß-lactamase (ESBL)-producing coliforms in a geriatric population and among haematology patients |
| title_short | Faecal prevalence of extended-spectrum ß-lactamase (ESBL)-producing coliforms in a geriatric population and among haematology patients |
| title_sort | faecal prevalence of extended spectrum ss lactamase esbl producing coliforms in a geriatric population and among haematology patients |
| topic | R Medicine |
| url | http://eprints.um.edu.my/1960/1/1.pdf |
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