Attenuated Total Reflection Fourier Transform Infrared (ATR FT-IR) Spectroscopy as an Analytical Method to Investigate the Secondary Structure of a Model Protein Embedded in Solid Lipid Matrices

Attenuated Total Reflection Fourier Transform Infrared (ATR FT-IR) Spectroscopy as an Analytical Method to Investigate the Secondary Structure of a Model Protein Embedded in Solid Lipid Matrices

Protein drugs may encounter conformational perturbations during the formulation processing of lipid-based solid dosage forms. In aqueous protein solutions, attenuated total reflection Fourier transform infrared (ATR FT-IR) spectroscopy can investigate these conformational changes following the subtr...

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Bibliographic Details
Main Authors:	Zeeshan, Farrukh, Tabbassum, Misbah, Jorgensen, Lene, Medlicott, Natalie J.
Format:	Article
Published:	SAGE Publications 2018
Subjects:	QD Chemistry RS Pharmacy and materia medica

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