Microfluidic production of bioactive fibrin micro-beads embedded in crosslinked collagen used as an injectable bulking agent for urinary incontinence treatment
Endoscopic injection of bulking agents has been widely used to treat urinary incontinence, often due to urethral sphincter complex insufficiency. The aim of the study was to develop a novel injectable bioactive collagen-fibrin bulking agent restoring long-term continence by functional muscle tissue...
Main Authors: | Vardar, Elif, Larsson, Hans M., Allazetta, Simone, Engelhardt, Eva Maria, Pinnagoda, Kalitha, Vythilingam, Ganesh, Hubbell, Jeffrey Alan, Lutolf, Matthias P., Frey, Peter |
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Format: | Article |
Published: |
Elsevier
2018
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