Tamarindus indica seeds improve carbohydrate and lipid metabolism: An in vivo study

Background: The tamarind seeds have a lot of nutrients that may be used to control cholesterol or glucose levels. Objective(s): The effects of tamarind seeds (T) on lipid and carbohydrate metabolism in rats were studied. Rats were offered basal diet (BD) with T (2%, 4% or 8%) or without T. Materials...

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Main Authors: Uchenna, Uzukwu Emmanuel, Shori, Amal Bakr, Baba, Ahmad Salihin
Format: Article
Published: Elsevier 2018
Subjects:
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author Uchenna, Uzukwu Emmanuel
Shori, Amal Bakr
Baba, Ahmad Salihin
author_facet Uchenna, Uzukwu Emmanuel
Shori, Amal Bakr
Baba, Ahmad Salihin
author_sort Uchenna, Uzukwu Emmanuel
collection UM
description Background: The tamarind seeds have a lot of nutrients that may be used to control cholesterol or glucose levels. Objective(s): The effects of tamarind seeds (T) on lipid and carbohydrate metabolism in rats were studied. Rats were offered basal diet (BD) with T (2%, 4% or 8%) or without T. Materials and methods: Feeding and growth performance in rats were measured and samples of liver and blood were analyzed for glycogen content and levels of cholesterol and glucose respectively. Results: The inclusion of T in the diet influences the feeding and growth performance in rats. The serum cholesterol level was reduced (p < 0.05) in Sprague Dawley (SD) rats fed on basal diet (BD) containing 4% and 8% T (0.24 ± 0.14 g/l and 0.31 ± 0.06 g/l respectively) compared to control (0.79 ± 0.04 g/l). The serum glucose levels in the spontaneous hypertensive rats (SHR) was lower (50.74 ± 2.50 mg/dl; p < 0.05) than control (93.52 ± 10.83 mg/dl) at 4% T. Incorporation of increasing doses of T resulted in linear increase of glycogen storage in livers of SD rats fed on BD and high sucrose diet. Conclusion: Tamarind seeds can lower blood glucose and serum cholesterol and enhance storage of glycogen in rats.
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spelling um.eprints-204442019-02-22T02:18:24Z http://eprints.um.edu.my/20444/ Tamarindus indica seeds improve carbohydrate and lipid metabolism: An in vivo study Uchenna, Uzukwu Emmanuel Shori, Amal Bakr Baba, Ahmad Salihin Q Science (General) QH Natural history Background: The tamarind seeds have a lot of nutrients that may be used to control cholesterol or glucose levels. Objective(s): The effects of tamarind seeds (T) on lipid and carbohydrate metabolism in rats were studied. Rats were offered basal diet (BD) with T (2%, 4% or 8%) or without T. Materials and methods: Feeding and growth performance in rats were measured and samples of liver and blood were analyzed for glycogen content and levels of cholesterol and glucose respectively. Results: The inclusion of T in the diet influences the feeding and growth performance in rats. The serum cholesterol level was reduced (p < 0.05) in Sprague Dawley (SD) rats fed on basal diet (BD) containing 4% and 8% T (0.24 ± 0.14 g/l and 0.31 ± 0.06 g/l respectively) compared to control (0.79 ± 0.04 g/l). The serum glucose levels in the spontaneous hypertensive rats (SHR) was lower (50.74 ± 2.50 mg/dl; p < 0.05) than control (93.52 ± 10.83 mg/dl) at 4% T. Incorporation of increasing doses of T resulted in linear increase of glycogen storage in livers of SD rats fed on BD and high sucrose diet. Conclusion: Tamarind seeds can lower blood glucose and serum cholesterol and enhance storage of glycogen in rats. Elsevier 2018 Article PeerReviewed Uchenna, Uzukwu Emmanuel and Shori, Amal Bakr and Baba, Ahmad Salihin (2018) Tamarindus indica seeds improve carbohydrate and lipid metabolism: An in vivo study. Journal of Ayurveda and Integrative Medicine, 9 (4). pp. 258-265. ISSN 0975-9476, DOI https://doi.org/10.1016/j.jaim.2017.06.004 <https://doi.org/10.1016/j.jaim.2017.06.004>. https://doi.org/10.1016/j.jaim.2017.06.004 doi:10.1016/j.jaim.2017.06.004
spellingShingle Q Science (General)
QH Natural history
Uchenna, Uzukwu Emmanuel
Shori, Amal Bakr
Baba, Ahmad Salihin
Tamarindus indica seeds improve carbohydrate and lipid metabolism: An in vivo study
title Tamarindus indica seeds improve carbohydrate and lipid metabolism: An in vivo study
title_full Tamarindus indica seeds improve carbohydrate and lipid metabolism: An in vivo study
title_fullStr Tamarindus indica seeds improve carbohydrate and lipid metabolism: An in vivo study
title_full_unstemmed Tamarindus indica seeds improve carbohydrate and lipid metabolism: An in vivo study
title_short Tamarindus indica seeds improve carbohydrate and lipid metabolism: An in vivo study
title_sort tamarindus indica seeds improve carbohydrate and lipid metabolism an in vivo study
topic Q Science (General)
QH Natural history
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AT shoriamalbakr tamarindusindicaseedsimprovecarbohydrateandlipidmetabolismaninvivostudy
AT babaahmadsalihin tamarindusindicaseedsimprovecarbohydrateandlipidmetabolismaninvivostudy