Choroidal thickness in Malaysian eyes with full-thickness macular holes
AIM: To compare choroidal thickness at the macula in eyes with unilateral idiopathic full-thickness macular holes (FTMH) with that of unaffected fellow eyes, and eyes of normal control patients. METHODS: Cross-sectional study. Thirty patients with unilateral idiopathic FTMH and thirty age, sex, and...
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Press of International Journal of Ophthalmology
2018
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| author | Tan, Chew Y. Vengadasalam, Selva Raja Samsudin, Amir Khaliddin, Nurliza |
| author_facet | Tan, Chew Y. Vengadasalam, Selva Raja Samsudin, Amir Khaliddin, Nurliza |
| author_sort | Tan, Chew Y. |
| collection | UM |
| description | AIM: To compare choroidal thickness at the macula in eyes with unilateral idiopathic full-thickness macular holes (FTMH) with that of unaffected fellow eyes, and eyes of normal control patients. METHODS: Cross-sectional study. Thirty patients with unilateral idiopathic FTMH and thirty age, sex, and race-matched controls were recruited. Axial lengths were measured using laser interferometry. Enhanced depth imaging optical coherence tomography images were obtained using Heidelberg spectral-domain optical coherence tomography. Choroidal thickness was measured at the fovea, and at 1 mm and 2 mm nasally, temporally, superiorly and inferiorly from the center of the fovea. Statistical analysis was performed using independent and paired t-tests, chi-square tests, and Pearson correlation tests (P<0.05). RESULTS: The mean subfoveal choroidal thickness was 201.0±44.0 μm in the FTMH group, 225.3±51.4 μm in the fellow eye group and 262.3±70.3 μm in the control group. The choroid was thinner in FTMH eyes at all locations when compared to control eyes (P<0.05). The fellow eye group also had thinner choroids than the control group at all locations except at 1 mm and 2 mm nasal to the fovea (P<0.05). Choroidal thickness in the FTMH group was lower than in the fellow eye group, but the differences were not statistically significant (P>0.05). Choroidal thickness was generally highest subfoveally and lowest nasally. Subfoveal choroidal thickness was negatively correlated with age (r=-0.278, P=0.032), and axial length (r=-0.328, P=0.011). CONCLUSION: Choroidal thickness is lower in both eyes of patients with unilateral FTMH compared to healthy control eyes. |
| first_indexed | 2024-03-06T05:51:32Z |
| format | Article |
| id | um.eprints-20547 |
| institution | Universiti Malaya |
| last_indexed | 2024-03-06T05:51:32Z |
| publishDate | 2018 |
| publisher | Press of International Journal of Ophthalmology |
| record_format | dspace |
| spelling | um.eprints-205472019-03-04T01:56:03Z http://eprints.um.edu.my/20547/ Choroidal thickness in Malaysian eyes with full-thickness macular holes Tan, Chew Y. Vengadasalam, Selva Raja Samsudin, Amir Khaliddin, Nurliza R Medicine AIM: To compare choroidal thickness at the macula in eyes with unilateral idiopathic full-thickness macular holes (FTMH) with that of unaffected fellow eyes, and eyes of normal control patients. METHODS: Cross-sectional study. Thirty patients with unilateral idiopathic FTMH and thirty age, sex, and race-matched controls were recruited. Axial lengths were measured using laser interferometry. Enhanced depth imaging optical coherence tomography images were obtained using Heidelberg spectral-domain optical coherence tomography. Choroidal thickness was measured at the fovea, and at 1 mm and 2 mm nasally, temporally, superiorly and inferiorly from the center of the fovea. Statistical analysis was performed using independent and paired t-tests, chi-square tests, and Pearson correlation tests (P<0.05). RESULTS: The mean subfoveal choroidal thickness was 201.0±44.0 μm in the FTMH group, 225.3±51.4 μm in the fellow eye group and 262.3±70.3 μm in the control group. The choroid was thinner in FTMH eyes at all locations when compared to control eyes (P<0.05). The fellow eye group also had thinner choroids than the control group at all locations except at 1 mm and 2 mm nasal to the fovea (P<0.05). Choroidal thickness in the FTMH group was lower than in the fellow eye group, but the differences were not statistically significant (P>0.05). Choroidal thickness was generally highest subfoveally and lowest nasally. Subfoveal choroidal thickness was negatively correlated with age (r=-0.278, P=0.032), and axial length (r=-0.328, P=0.011). CONCLUSION: Choroidal thickness is lower in both eyes of patients with unilateral FTMH compared to healthy control eyes. Press of International Journal of Ophthalmology 2018 Article PeerReviewed Tan, Chew Y. and Vengadasalam, Selva Raja and Samsudin, Amir and Khaliddin, Nurliza (2018) Choroidal thickness in Malaysian eyes with full-thickness macular holes. International Eye Science, 18 (3). pp. 401-405. ISSN 1672-5123, DOI https://doi.org/10.3980/j.issn.1672-5123.2018.3.01 <https://doi.org/10.3980/j.issn.1672-5123.2018.3.01>. http://ies.ijo.cn/gjykcn/ch/reader/view_abstract.aspx?file_no=201803001&flag=1 doi:10.3980/j.issn.1672-5123.2018.3.01 |
| spellingShingle | R Medicine Tan, Chew Y. Vengadasalam, Selva Raja Samsudin, Amir Khaliddin, Nurliza Choroidal thickness in Malaysian eyes with full-thickness macular holes |
| title | Choroidal thickness in Malaysian eyes with full-thickness macular holes |
| title_full | Choroidal thickness in Malaysian eyes with full-thickness macular holes |
| title_fullStr | Choroidal thickness in Malaysian eyes with full-thickness macular holes |
| title_full_unstemmed | Choroidal thickness in Malaysian eyes with full-thickness macular holes |
| title_short | Choroidal thickness in Malaysian eyes with full-thickness macular holes |
| title_sort | choroidal thickness in malaysian eyes with full thickness macular holes |
| topic | R Medicine |
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