Renewable resources-based approach to biantennary glycolipids
A new synthesis approach towards biantennary lipids of Guerbet glycoside type was developed based on oleic acid as sustainable resource. Functionalization of the double bond provided access to primary alcohols with α-branched C19-skeleton. Formulation studies with corresponding lactosides indicated...
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| Format: | Article |
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Elsevier
2018
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| _version_ | 1796961264833921024 |
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| author | Tabandeh, Mojtaba Salman, Abbas Abdulameer Goh, Ean Wai Heidelberg, Thorsten Hussen, Rusnah Syahila Duali |
| author_facet | Tabandeh, Mojtaba Salman, Abbas Abdulameer Goh, Ean Wai Heidelberg, Thorsten Hussen, Rusnah Syahila Duali |
| author_sort | Tabandeh, Mojtaba |
| collection | UM |
| description | A new synthesis approach towards biantennary lipids of Guerbet glycoside type was developed based on oleic acid as sustainable resource. Functionalization of the double bond provided access to primary alcohols with α-branched C19-skeleton. Formulation studies with corresponding lactosides indicated formation of vesicles with high assembly stability. A relatively narrow bimodal size distribution of the latter, which turns into a narrow unimodal distribution of small vesicles upon addition of an ionic cosurfactant, suggests potential for a vesicular drug delivery system. |
| first_indexed | 2024-03-06T05:51:38Z |
| format | Article |
| id | um.eprints-20584 |
| institution | Universiti Malaya |
| last_indexed | 2024-03-06T05:51:38Z |
| publishDate | 2018 |
| publisher | Elsevier |
| record_format | dspace |
| spelling | um.eprints-205842019-03-04T07:44:36Z http://eprints.um.edu.my/20584/ Renewable resources-based approach to biantennary glycolipids Tabandeh, Mojtaba Salman, Abbas Abdulameer Goh, Ean Wai Heidelberg, Thorsten Hussen, Rusnah Syahila Duali Q Science (General) QD Chemistry A new synthesis approach towards biantennary lipids of Guerbet glycoside type was developed based on oleic acid as sustainable resource. Functionalization of the double bond provided access to primary alcohols with α-branched C19-skeleton. Formulation studies with corresponding lactosides indicated formation of vesicles with high assembly stability. A relatively narrow bimodal size distribution of the latter, which turns into a narrow unimodal distribution of small vesicles upon addition of an ionic cosurfactant, suggests potential for a vesicular drug delivery system. Elsevier 2018 Article PeerReviewed Tabandeh, Mojtaba and Salman, Abbas Abdulameer and Goh, Ean Wai and Heidelberg, Thorsten and Hussen, Rusnah Syahila Duali (2018) Renewable resources-based approach to biantennary glycolipids. Chemistry and Physics of Lipids, 212. pp. 111-119. ISSN 0009-3084, DOI https://doi.org/10.1016/j.chemphyslip.2018.01.011 <https://doi.org/10.1016/j.chemphyslip.2018.01.011>. https://doi.org/10.1016/j.chemphyslip.2018.01.011 doi:10.1016/j.chemphyslip.2018.01.011 |
| spellingShingle | Q Science (General) QD Chemistry Tabandeh, Mojtaba Salman, Abbas Abdulameer Goh, Ean Wai Heidelberg, Thorsten Hussen, Rusnah Syahila Duali Renewable resources-based approach to biantennary glycolipids |
| title | Renewable resources-based approach to biantennary glycolipids |
| title_full | Renewable resources-based approach to biantennary glycolipids |
| title_fullStr | Renewable resources-based approach to biantennary glycolipids |
| title_full_unstemmed | Renewable resources-based approach to biantennary glycolipids |
| title_short | Renewable resources-based approach to biantennary glycolipids |
| title_sort | renewable resources based approach to biantennary glycolipids |
| topic | Q Science (General) QD Chemistry |
| work_keys_str_mv | AT tabandehmojtaba renewableresourcesbasedapproachtobiantennaryglycolipids AT salmanabbasabdulameer renewableresourcesbasedapproachtobiantennaryglycolipids AT goheanwai renewableresourcesbasedapproachtobiantennaryglycolipids AT heidelbergthorsten renewableresourcesbasedapproachtobiantennaryglycolipids AT hussenrusnahsyahiladuali renewableresourcesbasedapproachtobiantennaryglycolipids |