Highly-ordered TiO 2 nanotubes decorated with Ag 2 O nanoparticles for improved biofunctionality of Ti6Al4V

The nanotubular arrays of titanium dioxide (TiO2 NTs) have recently received considerable interest for fabrication of dental and orthopedic implants. However, their antibacterial activity requires substantial improvement for the potential infections minimization, without compromise of their biocompa...

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Main Authors: Sarraf, Masoud, Dabbagh, Ali, Bushroa, Abdul Razak, Mahmoodian, Reza, Nasiri-Tabrizi, Bahman, Hosseini, Hamid Reza Madaah, Saber-Samandari, Saeed, Abu Kasim, Noor Hayaty, Abdullah, Hadijah, Sukiman, Nazatul Liana
Format: Article
Published: Elsevier 2018
Subjects:
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author Sarraf, Masoud
Dabbagh, Ali
Bushroa, Abdul Razak
Mahmoodian, Reza
Nasiri-Tabrizi, Bahman
Hosseini, Hamid Reza Madaah
Saber-Samandari, Saeed
Abu Kasim, Noor Hayaty
Abdullah, Hadijah
Sukiman, Nazatul Liana
author_facet Sarraf, Masoud
Dabbagh, Ali
Bushroa, Abdul Razak
Mahmoodian, Reza
Nasiri-Tabrizi, Bahman
Hosseini, Hamid Reza Madaah
Saber-Samandari, Saeed
Abu Kasim, Noor Hayaty
Abdullah, Hadijah
Sukiman, Nazatul Liana
author_sort Sarraf, Masoud
collection UM
description The nanotubular arrays of titanium dioxide (TiO2 NTs) have recently received considerable interest for fabrication of dental and orthopedic implants. However, their antibacterial activity requires substantial improvement for the potential infections minimization, without compromise of their biocompatibility. In this work, TiO2 NTs were developed on Ti6Al4V substrates via anodization at a constant potential of 60 V for 60 min, followed by heat treatment at 500 °C for 90 min. Physical vapor deposition (PVD) was further employed to decorate silver oxide nanoparticles (Ag2O NPs) on the nanotubular edges. The results indicated that the highly-ordered TiO2 NTs with decorated Ag2O NPs could promote the apatite formation and kill 100% of the Escherichia coli (E. coli) bacteria within 2 h. Moreover, proliferation of the human osteoblast cells (HOb) was continuously stimulated throughout culture on the Ag2O NPs-decorated TiO2 NTs. The variation in the viability of HOb cells was statistically insignificant at differed cultivation intervals, indicating the negligible effect of the decorated Ag2O NPs on the osseointegration of these implant materials.
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spelling um.eprints-207652019-03-19T07:21:58Z http://eprints.um.edu.my/20765/ Highly-ordered TiO 2 nanotubes decorated with Ag 2 O nanoparticles for improved biofunctionality of Ti6Al4V Sarraf, Masoud Dabbagh, Ali Bushroa, Abdul Razak Mahmoodian, Reza Nasiri-Tabrizi, Bahman Hosseini, Hamid Reza Madaah Saber-Samandari, Saeed Abu Kasim, Noor Hayaty Abdullah, Hadijah Sukiman, Nazatul Liana RK Dentistry TJ Mechanical engineering and machinery The nanotubular arrays of titanium dioxide (TiO2 NTs) have recently received considerable interest for fabrication of dental and orthopedic implants. However, their antibacterial activity requires substantial improvement for the potential infections minimization, without compromise of their biocompatibility. In this work, TiO2 NTs were developed on Ti6Al4V substrates via anodization at a constant potential of 60 V for 60 min, followed by heat treatment at 500 °C for 90 min. Physical vapor deposition (PVD) was further employed to decorate silver oxide nanoparticles (Ag2O NPs) on the nanotubular edges. The results indicated that the highly-ordered TiO2 NTs with decorated Ag2O NPs could promote the apatite formation and kill 100% of the Escherichia coli (E. coli) bacteria within 2 h. Moreover, proliferation of the human osteoblast cells (HOb) was continuously stimulated throughout culture on the Ag2O NPs-decorated TiO2 NTs. The variation in the viability of HOb cells was statistically insignificant at differed cultivation intervals, indicating the negligible effect of the decorated Ag2O NPs on the osseointegration of these implant materials. Elsevier 2018 Article PeerReviewed Sarraf, Masoud and Dabbagh, Ali and Bushroa, Abdul Razak and Mahmoodian, Reza and Nasiri-Tabrizi, Bahman and Hosseini, Hamid Reza Madaah and Saber-Samandari, Saeed and Abu Kasim, Noor Hayaty and Abdullah, Hadijah and Sukiman, Nazatul Liana (2018) Highly-ordered TiO 2 nanotubes decorated with Ag 2 O nanoparticles for improved biofunctionality of Ti6Al4V. Surface and Coatings Technology, 349. pp. 1008-1017. ISSN 0257-8972, DOI https://doi.org/10.1016/j.surfcoat.2018.06.054 <https://doi.org/10.1016/j.surfcoat.2018.06.054>. https://doi.org/10.1016/j.surfcoat.2018.06.054 doi:10.1016/j.surfcoat.2018.06.054
spellingShingle RK Dentistry
TJ Mechanical engineering and machinery
Sarraf, Masoud
Dabbagh, Ali
Bushroa, Abdul Razak
Mahmoodian, Reza
Nasiri-Tabrizi, Bahman
Hosseini, Hamid Reza Madaah
Saber-Samandari, Saeed
Abu Kasim, Noor Hayaty
Abdullah, Hadijah
Sukiman, Nazatul Liana
Highly-ordered TiO 2 nanotubes decorated with Ag 2 O nanoparticles for improved biofunctionality of Ti6Al4V
title Highly-ordered TiO 2 nanotubes decorated with Ag 2 O nanoparticles for improved biofunctionality of Ti6Al4V
title_full Highly-ordered TiO 2 nanotubes decorated with Ag 2 O nanoparticles for improved biofunctionality of Ti6Al4V
title_fullStr Highly-ordered TiO 2 nanotubes decorated with Ag 2 O nanoparticles for improved biofunctionality of Ti6Al4V
title_full_unstemmed Highly-ordered TiO 2 nanotubes decorated with Ag 2 O nanoparticles for improved biofunctionality of Ti6Al4V
title_short Highly-ordered TiO 2 nanotubes decorated with Ag 2 O nanoparticles for improved biofunctionality of Ti6Al4V
title_sort highly ordered tio 2 nanotubes decorated with ag 2 o nanoparticles for improved biofunctionality of ti6al4v
topic RK Dentistry
TJ Mechanical engineering and machinery
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