Silver oxide nanoparticles-decorated tantala nanotubes for enhanced antibacterial activity and osseointegration of Ti6Al4V
A long-term antibacterial activity of implants without compromising their biocompatibility is highly desirable to minimize the biomaterial-associated infections. Although tantalum oxide nanotubes (Ta2O5 NTs) are promising coating materials for orthodontics and orthopedics applications, their insuffi...
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| Format: | Article |
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Elsevier
2018
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| _version_ | 1796961299450560512 |
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| author | Sarraf, Masoud Dabbagh, Ali Bushroa, Abdul Razak Nasiri-Tabrizi, Bahman Hosseini, Hamid Reza Madaah Saber-Samandari, Saeed Abu Kasim, Noor Hayaty Lum, Kah Yean Sukiman, Nazatul Liana |
| author_facet | Sarraf, Masoud Dabbagh, Ali Bushroa, Abdul Razak Nasiri-Tabrizi, Bahman Hosseini, Hamid Reza Madaah Saber-Samandari, Saeed Abu Kasim, Noor Hayaty Lum, Kah Yean Sukiman, Nazatul Liana |
| author_sort | Sarraf, Masoud |
| collection | UM |
| description | A long-term antibacterial activity of implants without compromising their biocompatibility is highly desirable to minimize the biomaterial-associated infections. Although tantalum oxide nanotubes (Ta2O5 NTs) are promising coating materials for orthodontics and orthopedics applications, their insufficient antibacterial activity retains vulnerability to post-implantation infections. This study aimed to endow antibacterial characteristics to the Ta2O5 NTs-coated Ti6Al4V substrates by decoration of silver oxide nanoparticles (Ag2O NPs). The well-adherent Ta2O5 NTs were grown via anodization of a pure tantalum (Ta) layer coated by physical vapor deposition (PVD) on the Ti6Al4V substrates. The Ag2O NPs were then decorated on the edges and walls of nanotubes through a secondary PVD under controlled conditions. The silver oxide nanoparticles-decorated tantala nanotubes (Ag2O NPs-decorated Ta2O5 NTs) promoted the formation of bone-like apatite layer and significantly reduced the viability of Escherichia coli (E. coli) cells. The prepared coating also increased the density and spreading of osteoblast cells in comparison to bare substrate. These results suggest that decorating the Ta2O5 NTs with Ag2O nanoparticles could improve antibacterial activity and the osseointegration of Ti6Al4V implants. |
| first_indexed | 2024-03-06T05:52:14Z |
| format | Article |
| id | um.eprints-20766 |
| institution | Universiti Malaya |
| last_indexed | 2024-03-06T05:52:14Z |
| publishDate | 2018 |
| publisher | Elsevier |
| record_format | dspace |
| spelling | um.eprints-207662019-12-05T05:48:48Z http://eprints.um.edu.my/20766/ Silver oxide nanoparticles-decorated tantala nanotubes for enhanced antibacterial activity and osseointegration of Ti6Al4V Sarraf, Masoud Dabbagh, Ali Bushroa, Abdul Razak Nasiri-Tabrizi, Bahman Hosseini, Hamid Reza Madaah Saber-Samandari, Saeed Abu Kasim, Noor Hayaty Lum, Kah Yean Sukiman, Nazatul Liana R Medicine RK Dentistry TJ Mechanical engineering and machinery A long-term antibacterial activity of implants without compromising their biocompatibility is highly desirable to minimize the biomaterial-associated infections. Although tantalum oxide nanotubes (Ta2O5 NTs) are promising coating materials for orthodontics and orthopedics applications, their insufficient antibacterial activity retains vulnerability to post-implantation infections. This study aimed to endow antibacterial characteristics to the Ta2O5 NTs-coated Ti6Al4V substrates by decoration of silver oxide nanoparticles (Ag2O NPs). The well-adherent Ta2O5 NTs were grown via anodization of a pure tantalum (Ta) layer coated by physical vapor deposition (PVD) on the Ti6Al4V substrates. The Ag2O NPs were then decorated on the edges and walls of nanotubes through a secondary PVD under controlled conditions. The silver oxide nanoparticles-decorated tantala nanotubes (Ag2O NPs-decorated Ta2O5 NTs) promoted the formation of bone-like apatite layer and significantly reduced the viability of Escherichia coli (E. coli) cells. The prepared coating also increased the density and spreading of osteoblast cells in comparison to bare substrate. These results suggest that decorating the Ta2O5 NTs with Ag2O nanoparticles could improve antibacterial activity and the osseointegration of Ti6Al4V implants. Elsevier 2018 Article PeerReviewed Sarraf, Masoud and Dabbagh, Ali and Bushroa, Abdul Razak and Nasiri-Tabrizi, Bahman and Hosseini, Hamid Reza Madaah and Saber-Samandari, Saeed and Abu Kasim, Noor Hayaty and Lum, Kah Yean and Sukiman, Nazatul Liana (2018) Silver oxide nanoparticles-decorated tantala nanotubes for enhanced antibacterial activity and osseointegration of Ti6Al4V. Materials & Design, 154. pp. 28-40. ISSN 0261-3069, DOI https://doi.org/10.1016/j.matdes.2018.05.025 <https://doi.org/10.1016/j.matdes.2018.05.025>. https://doi.org/10.1016/j.matdes.2018.05.025 doi:10.1016/j.matdes.2018.05.025 |
| spellingShingle | R Medicine RK Dentistry TJ Mechanical engineering and machinery Sarraf, Masoud Dabbagh, Ali Bushroa, Abdul Razak Nasiri-Tabrizi, Bahman Hosseini, Hamid Reza Madaah Saber-Samandari, Saeed Abu Kasim, Noor Hayaty Lum, Kah Yean Sukiman, Nazatul Liana Silver oxide nanoparticles-decorated tantala nanotubes for enhanced antibacterial activity and osseointegration of Ti6Al4V |
| title | Silver oxide nanoparticles-decorated tantala nanotubes for enhanced antibacterial activity and osseointegration of Ti6Al4V |
| title_full | Silver oxide nanoparticles-decorated tantala nanotubes for enhanced antibacterial activity and osseointegration of Ti6Al4V |
| title_fullStr | Silver oxide nanoparticles-decorated tantala nanotubes for enhanced antibacterial activity and osseointegration of Ti6Al4V |
| title_full_unstemmed | Silver oxide nanoparticles-decorated tantala nanotubes for enhanced antibacterial activity and osseointegration of Ti6Al4V |
| title_short | Silver oxide nanoparticles-decorated tantala nanotubes for enhanced antibacterial activity and osseointegration of Ti6Al4V |
| title_sort | silver oxide nanoparticles decorated tantala nanotubes for enhanced antibacterial activity and osseointegration of ti6al4v |
| topic | R Medicine RK Dentistry TJ Mechanical engineering and machinery |
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