Characterization of biogenic hydroxyapatite derived from animal bones for biomedical applications
In this work, the viability of producing biogenic hydroxyapatite from bio-waste animal bones, namely bovine (cow), caprine (goat) and galline (chicken), through a heat treatment process has been investigated. The animal bones were locally sourced, cleaned to remove collagen and subsequently heat tre...
| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Publicado em: |
Elsevier
2018
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| Assuntos: |
| _version_ | 1825721593783910400 |
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| author | Ramesh, Singh Loo, Zi Zhen Tan, Chou Yong Chew, Wai Jin Kelvin Ching, Yern Chee Tarlochan, Faris Chandran, Hari Krishnasamy, Sivakumar Bang, Le Thi Sarhan, Ahmed Aly Diaa Mohammed |
| author_facet | Ramesh, Singh Loo, Zi Zhen Tan, Chou Yong Chew, Wai Jin Kelvin Ching, Yern Chee Tarlochan, Faris Chandran, Hari Krishnasamy, Sivakumar Bang, Le Thi Sarhan, Ahmed Aly Diaa Mohammed |
| author_sort | Ramesh, Singh |
| collection | UM |
| description | In this work, the viability of producing biogenic hydroxyapatite from bio-waste animal bones, namely bovine (cow), caprine (goat) and galline (chicken), through a heat treatment process has been investigated. The animal bones were locally sourced, cleaned to remove collagen and subsequently heat treated in air atmosphere at different temperatures ranging from 600 °C to 1000 °C. From the range of sintering temperatures investigated, it was found that hydroxyapatite derived from bovine bone showed good thermal stability while those produced from caprine and galline bones exhibited phase instability with traces of tri-calcium phosphate (TCP) being detected after heat treatment beyond 700 °C. The porous nature of the bone samples can be observed from the microstructures obtained and supported by low relative density. Heating the bovine and caprine bones at selected temperatures yielded porous HA body, having hardness values that are comparable with human cortical bone. However, the sintered galline bone sample showed higher porosity levels and low hardness when compared to the other two bone types. |
| first_indexed | 2024-03-06T05:52:43Z |
| format | Article |
| id | um.eprints-20931 |
| institution | Universiti Malaya |
| last_indexed | 2024-03-06T05:52:43Z |
| publishDate | 2018 |
| publisher | Elsevier |
| record_format | dspace |
| spelling | um.eprints-209312019-04-16T07:50:48Z http://eprints.um.edu.my/20931/ Characterization of biogenic hydroxyapatite derived from animal bones for biomedical applications Ramesh, Singh Loo, Zi Zhen Tan, Chou Yong Chew, Wai Jin Kelvin Ching, Yern Chee Tarlochan, Faris Chandran, Hari Krishnasamy, Sivakumar Bang, Le Thi Sarhan, Ahmed Aly Diaa Mohammed R Medicine TJ Mechanical engineering and machinery In this work, the viability of producing biogenic hydroxyapatite from bio-waste animal bones, namely bovine (cow), caprine (goat) and galline (chicken), through a heat treatment process has been investigated. The animal bones were locally sourced, cleaned to remove collagen and subsequently heat treated in air atmosphere at different temperatures ranging from 600 °C to 1000 °C. From the range of sintering temperatures investigated, it was found that hydroxyapatite derived from bovine bone showed good thermal stability while those produced from caprine and galline bones exhibited phase instability with traces of tri-calcium phosphate (TCP) being detected after heat treatment beyond 700 °C. The porous nature of the bone samples can be observed from the microstructures obtained and supported by low relative density. Heating the bovine and caprine bones at selected temperatures yielded porous HA body, having hardness values that are comparable with human cortical bone. However, the sintered galline bone sample showed higher porosity levels and low hardness when compared to the other two bone types. Elsevier 2018 Article PeerReviewed Ramesh, Singh and Loo, Zi Zhen and Tan, Chou Yong and Chew, Wai Jin Kelvin and Ching, Yern Chee and Tarlochan, Faris and Chandran, Hari and Krishnasamy, Sivakumar and Bang, Le Thi and Sarhan, Ahmed Aly Diaa Mohammed (2018) Characterization of biogenic hydroxyapatite derived from animal bones for biomedical applications. Ceramics International, 44 (9). pp. 10525-10530. ISSN 0272-8842, DOI https://doi.org/10.1016/j.ceramint.2018.03.072 <https://doi.org/10.1016/j.ceramint.2018.03.072>. https://doi.org/10.1016/j.ceramint.2018.03.072 doi:10.1016/j.ceramint.2018.03.072 |
| spellingShingle | R Medicine TJ Mechanical engineering and machinery Ramesh, Singh Loo, Zi Zhen Tan, Chou Yong Chew, Wai Jin Kelvin Ching, Yern Chee Tarlochan, Faris Chandran, Hari Krishnasamy, Sivakumar Bang, Le Thi Sarhan, Ahmed Aly Diaa Mohammed Characterization of biogenic hydroxyapatite derived from animal bones for biomedical applications |
| title | Characterization of biogenic hydroxyapatite derived from animal bones for biomedical applications |
| title_full | Characterization of biogenic hydroxyapatite derived from animal bones for biomedical applications |
| title_fullStr | Characterization of biogenic hydroxyapatite derived from animal bones for biomedical applications |
| title_full_unstemmed | Characterization of biogenic hydroxyapatite derived from animal bones for biomedical applications |
| title_short | Characterization of biogenic hydroxyapatite derived from animal bones for biomedical applications |
| title_sort | characterization of biogenic hydroxyapatite derived from animal bones for biomedical applications |
| topic | R Medicine TJ Mechanical engineering and machinery |
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