Identification and characterization of neutralization epitopes at VP2 and VP1 of enterovirus A71

Identification and characterization of neutralization epitopes at VP2 and VP1 of enterovirus A71

Enterovirus A71 (EV-A71) neutralization escape mutants were generated with monoclonal antibody MAB979 (Millipore). The VP2-T141I and VP1-D14N substitutions were identified. Using reverse genetics, infectious clones with these substitutions were constructed and tested by neutralization assay with imm...

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Bibliographic Details
Main Authors:	Nik Nadia, Nik Mohd Nasir, Tan, Chee Wah, Ong, Kien Chai, Sam, I-Ching, Chan, Yoke Fun
Format:	Article
Published:	Wiley 2018
Subjects:	R Medicine

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