Saccharin and tert-Butyl Nitrite: Cheap and Efficient Reagents for the Synthesis of 1,2,3-Benzotriazine-4-(3H)-ones from 2-Aminobenzamides under Metal-Free Conditions
A mild and eco-friendly protocol for the synthesis of 1,2,3-benzotriazine-4-(3H)-ones is described using saccharin as a cheap and efficient catalyst and tert-butyl nitrite as a diazotization reagent for the first time. The current method has advantages such as cost effectiveness, energy efficiency,...
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| Format: | Article |
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CSIRO Publishing
2018
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| _version_ | 1796961478130008064 |
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| author | Khaligh, Nader Ghaffari Johan, Mohd Rafie Juan, Joon Ching |
| author_facet | Khaligh, Nader Ghaffari Johan, Mohd Rafie Juan, Joon Ching |
| author_sort | Khaligh, Nader Ghaffari |
| collection | UM |
| description | A mild and eco-friendly protocol for the synthesis of 1,2,3-benzotriazine-4-(3H)-ones is described using saccharin as a cheap and efficient catalyst and tert-butyl nitrite as a diazotization reagent for the first time. The current method has advantages such as cost effectiveness, energy efficiency, and simple experimental procedure, good yield of the desired product, and metal-free and environmentally benign conditions. |
| first_indexed | 2024-03-06T05:54:42Z |
| format | Article |
| id | um.eprints-21642 |
| institution | Universiti Malaya |
| last_indexed | 2024-03-06T05:54:42Z |
| publishDate | 2018 |
| publisher | CSIRO Publishing |
| record_format | dspace |
| spelling | um.eprints-216422019-07-16T08:23:47Z http://eprints.um.edu.my/21642/ Saccharin and tert-Butyl Nitrite: Cheap and Efficient Reagents for the Synthesis of 1,2,3-Benzotriazine-4-(3H)-ones from 2-Aminobenzamides under Metal-Free Conditions Khaligh, Nader Ghaffari Johan, Mohd Rafie Juan, Joon Ching QD Chemistry TA Engineering (General). Civil engineering (General) A mild and eco-friendly protocol for the synthesis of 1,2,3-benzotriazine-4-(3H)-ones is described using saccharin as a cheap and efficient catalyst and tert-butyl nitrite as a diazotization reagent for the first time. The current method has advantages such as cost effectiveness, energy efficiency, and simple experimental procedure, good yield of the desired product, and metal-free and environmentally benign conditions. CSIRO Publishing 2018 Article PeerReviewed Khaligh, Nader Ghaffari and Johan, Mohd Rafie and Juan, Joon Ching (2018) Saccharin and tert-Butyl Nitrite: Cheap and Efficient Reagents for the Synthesis of 1,2,3-Benzotriazine-4-(3H)-ones from 2-Aminobenzamides under Metal-Free Conditions. Australian Journal of Chemistry, 71 (3). pp. 186-189. ISSN 0004-9425, DOI https://doi.org/10.1071/CH17590 <https://doi.org/10.1071/CH17590>. https://doi.org/10.1071/CH17590 doi:10.1071/CH17590 |
| spellingShingle | QD Chemistry TA Engineering (General). Civil engineering (General) Khaligh, Nader Ghaffari Johan, Mohd Rafie Juan, Joon Ching Saccharin and tert-Butyl Nitrite: Cheap and Efficient Reagents for the Synthesis of 1,2,3-Benzotriazine-4-(3H)-ones from 2-Aminobenzamides under Metal-Free Conditions |
| title | Saccharin and tert-Butyl Nitrite: Cheap and Efficient Reagents for the Synthesis of 1,2,3-Benzotriazine-4-(3H)-ones from 2-Aminobenzamides under Metal-Free Conditions |
| title_full | Saccharin and tert-Butyl Nitrite: Cheap and Efficient Reagents for the Synthesis of 1,2,3-Benzotriazine-4-(3H)-ones from 2-Aminobenzamides under Metal-Free Conditions |
| title_fullStr | Saccharin and tert-Butyl Nitrite: Cheap and Efficient Reagents for the Synthesis of 1,2,3-Benzotriazine-4-(3H)-ones from 2-Aminobenzamides under Metal-Free Conditions |
| title_full_unstemmed | Saccharin and tert-Butyl Nitrite: Cheap and Efficient Reagents for the Synthesis of 1,2,3-Benzotriazine-4-(3H)-ones from 2-Aminobenzamides under Metal-Free Conditions |
| title_short | Saccharin and tert-Butyl Nitrite: Cheap and Efficient Reagents for the Synthesis of 1,2,3-Benzotriazine-4-(3H)-ones from 2-Aminobenzamides under Metal-Free Conditions |
| title_sort | saccharin and tert butyl nitrite cheap and efficient reagents for the synthesis of 1 2 3 benzotriazine 4 3h ones from 2 aminobenzamides under metal free conditions |
| topic | QD Chemistry TA Engineering (General). Civil engineering (General) |
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