Measurement of coronary bifurcation angle with coronary CT angiography: A phantom study

Purpose: Accurate determination of the bifurcation angle and correlation with plaque buildup may lead to the prediction of coronary artery disease (CAD). This work evaluates two techniques to measure bifurcation angles in 3D space using coronary computed tomography angiography (CCTA). Materials and...

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Main Authors: Givehchi, Sogol, Safari, Mohammad Javad, Tan, Sock Keow, Shah, Mohammad Nazri Md, Sani, Fadhli Mohamed, Raja Aman, Raja Rizal Azman, Sun, Zhonghua, Yeong, Chai Hong, Ng, Kwan Hoong, Wong, Jeannie Hsiu Ding
Format: Article
Published: Elsevier 2018
Subjects:
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author Givehchi, Sogol
Safari, Mohammad Javad
Tan, Sock Keow
Shah, Mohammad Nazri Md
Sani, Fadhli Mohamed
Raja Aman, Raja Rizal Azman
Sun, Zhonghua
Yeong, Chai Hong
Ng, Kwan Hoong
Wong, Jeannie Hsiu Ding
author_facet Givehchi, Sogol
Safari, Mohammad Javad
Tan, Sock Keow
Shah, Mohammad Nazri Md
Sani, Fadhli Mohamed
Raja Aman, Raja Rizal Azman
Sun, Zhonghua
Yeong, Chai Hong
Ng, Kwan Hoong
Wong, Jeannie Hsiu Ding
author_sort Givehchi, Sogol
collection UM
description Purpose: Accurate determination of the bifurcation angle and correlation with plaque buildup may lead to the prediction of coronary artery disease (CAD). This work evaluates two techniques to measure bifurcation angles in 3D space using coronary computed tomography angiography (CCTA). Materials and Methods: Nine phantoms were fabricated with different bifurcation angles ranging from 55.3° to 134.5°. General X-ray and CCTA were employed to acquire 2D and 3D images of the bifurcation phantoms, respectively. Multiplanar reformation (MPR) and volume rendering technique (VRT) were used to measure the bifurcation angle between the left anterior descending (LAD) and left circumflex arteries (LCx). The measured angles were compared with the true values to determine the accuracy of each measurement technique. Inter-observer variability was evaluated. The two techniques were further applied on 50 clinical CCTA cases to verify its clinical value. Results: In the phantom setting, the mean absolute differences calculated between the true and measured angles by MPR and VRT were 2.4° ± 2.2° and 3.8° ± 2.9° respectively. Strong correlation was found between the true and measured bifurcation angles. Furthermore, no significant differences were found between the bifurcation angles measured using either technique. In clinical settings, large difference of 12.0° ± 10.6° was found between the two techniques. Conclusion: In the phantom setting, both techniques demonstrated a significant correlation to the true bifurcation angle. Despite the lack of agreement of the two techniques in the clinical context, our findings in phantoms suggest that MPR should be preferred to VRT for the measurement of coronary bifurcation angle by CCTA.
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spelling um.eprints-220192020-01-03T04:09:49Z http://eprints.um.edu.my/22019/ Measurement of coronary bifurcation angle with coronary CT angiography: A phantom study Givehchi, Sogol Safari, Mohammad Javad Tan, Sock Keow Shah, Mohammad Nazri Md Sani, Fadhli Mohamed Raja Aman, Raja Rizal Azman Sun, Zhonghua Yeong, Chai Hong Ng, Kwan Hoong Wong, Jeannie Hsiu Ding R Medicine Purpose: Accurate determination of the bifurcation angle and correlation with plaque buildup may lead to the prediction of coronary artery disease (CAD). This work evaluates two techniques to measure bifurcation angles in 3D space using coronary computed tomography angiography (CCTA). Materials and Methods: Nine phantoms were fabricated with different bifurcation angles ranging from 55.3° to 134.5°. General X-ray and CCTA were employed to acquire 2D and 3D images of the bifurcation phantoms, respectively. Multiplanar reformation (MPR) and volume rendering technique (VRT) were used to measure the bifurcation angle between the left anterior descending (LAD) and left circumflex arteries (LCx). The measured angles were compared with the true values to determine the accuracy of each measurement technique. Inter-observer variability was evaluated. The two techniques were further applied on 50 clinical CCTA cases to verify its clinical value. Results: In the phantom setting, the mean absolute differences calculated between the true and measured angles by MPR and VRT were 2.4° ± 2.2° and 3.8° ± 2.9° respectively. Strong correlation was found between the true and measured bifurcation angles. Furthermore, no significant differences were found between the bifurcation angles measured using either technique. In clinical settings, large difference of 12.0° ± 10.6° was found between the two techniques. Conclusion: In the phantom setting, both techniques demonstrated a significant correlation to the true bifurcation angle. Despite the lack of agreement of the two techniques in the clinical context, our findings in phantoms suggest that MPR should be preferred to VRT for the measurement of coronary bifurcation angle by CCTA. Elsevier 2018 Article PeerReviewed Givehchi, Sogol and Safari, Mohammad Javad and Tan, Sock Keow and Shah, Mohammad Nazri Md and Sani, Fadhli Mohamed and Raja Aman, Raja Rizal Azman and Sun, Zhonghua and Yeong, Chai Hong and Ng, Kwan Hoong and Wong, Jeannie Hsiu Ding (2018) Measurement of coronary bifurcation angle with coronary CT angiography: A phantom study. Physica Medica, 45. pp. 198-204. ISSN 1120-1797, DOI https://doi.org/10.1016/j.ejmp.2017.09.137 <https://doi.org/10.1016/j.ejmp.2017.09.137>. https://doi.org/10.1016/j.ejmp.2017.09.137 doi:10.1016/j.ejmp.2017.09.137
spellingShingle R Medicine
Givehchi, Sogol
Safari, Mohammad Javad
Tan, Sock Keow
Shah, Mohammad Nazri Md
Sani, Fadhli Mohamed
Raja Aman, Raja Rizal Azman
Sun, Zhonghua
Yeong, Chai Hong
Ng, Kwan Hoong
Wong, Jeannie Hsiu Ding
Measurement of coronary bifurcation angle with coronary CT angiography: A phantom study
title Measurement of coronary bifurcation angle with coronary CT angiography: A phantom study
title_full Measurement of coronary bifurcation angle with coronary CT angiography: A phantom study
title_fullStr Measurement of coronary bifurcation angle with coronary CT angiography: A phantom study
title_full_unstemmed Measurement of coronary bifurcation angle with coronary CT angiography: A phantom study
title_short Measurement of coronary bifurcation angle with coronary CT angiography: A phantom study
title_sort measurement of coronary bifurcation angle with coronary ct angiography a phantom study
topic R Medicine
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