SILAC-based phosphoproteomics reveals an inhibitory role of KSR1 in p53 transcriptional activity via modulation of DBC1

Background:We have previously identified kinase suppressor of ras-1 (KSR1) as a potential regulatory gene in breast cancer. KSR1, originally described as a novel protein kinase, has a role in activation of mitogen-activated protein kinases. Emerging evidence has shown that KSR1 may have dual functio...

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Bibliographic Details
Main Authors: Zhang, H., Xu, Y., Filipovic, A., Lit, Lei Cheng, Koo, C.Y., Stebbing, J., Giamas, G.
Format: Article
Published: Springer Nature 2013
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