Polarized Light-Based Cancer Cell Detection Techniques: A Review

Cancer is becoming raging phenomenon in clinical and pharmaceutical studies worldwide. It can be diagnosed by several step, including physical examination, blood or serum tests, and medical screening and imaging. Screening and imaging used to only be recommended if clear symptoms were observed, and...

Full description

Bibliographic Details
Main Authors: Tukimin, Siti Nurainie, Karman, Salmah, Ahmad, Mohd Yazed, Wan Kamarul Zaman, Wan Safwani
Format: Article
Published: Institute of Electrical and Electronics Engineers (IEEE) 2019
Subjects:
_version_ 1825722020325752832
author Tukimin, Siti Nurainie
Karman, Salmah
Ahmad, Mohd Yazed
Wan Kamarul Zaman, Wan Safwani
author_facet Tukimin, Siti Nurainie
Karman, Salmah
Ahmad, Mohd Yazed
Wan Kamarul Zaman, Wan Safwani
author_sort Tukimin, Siti Nurainie
collection UM
description Cancer is becoming raging phenomenon in clinical and pharmaceutical studies worldwide. It can be diagnosed by several step, including physical examination, blood or serum tests, and medical screening and imaging. Screening and imaging used to only be recommended if clear symptoms were observed, and positive results obtained from a blood test analysis were only significant if there was a high level of cancer markers observed. Optical biosensors are currently being developed that may be ideal for sensitive, selective and label free detection but burdensome and sophisticated. Recent studies of interest rely more on the application of nanomaterial (for indirect biochemical assays) than direct testing for in situ discrimination of the morphology of normal and cancerous cells. This review will be devoted to a description of the most recent developments of polarized light-based cancer cell/biomarker detection devices. These devices mostly operate based on a degree of polarization (DOP) and angle of polarization (AOP) of light parameters in separate devices. The main aim of this review is to provide an in-depth insight into the future use of device that measures the AOP in a single integrated device for cancer cell/tissue detection. © 2001-2012 IEEE.
first_indexed 2024-03-06T05:59:16Z
format Article
id um.eprints-23223
institution Universiti Malaya
last_indexed 2024-03-06T05:59:16Z
publishDate 2019
publisher Institute of Electrical and Electronics Engineers (IEEE)
record_format dspace
spelling um.eprints-232232019-12-16T03:40:59Z http://eprints.um.edu.my/23223/ Polarized Light-Based Cancer Cell Detection Techniques: A Review Tukimin, Siti Nurainie Karman, Salmah Ahmad, Mohd Yazed Wan Kamarul Zaman, Wan Safwani R Medicine TA Engineering (General). Civil engineering (General) Cancer is becoming raging phenomenon in clinical and pharmaceutical studies worldwide. It can be diagnosed by several step, including physical examination, blood or serum tests, and medical screening and imaging. Screening and imaging used to only be recommended if clear symptoms were observed, and positive results obtained from a blood test analysis were only significant if there was a high level of cancer markers observed. Optical biosensors are currently being developed that may be ideal for sensitive, selective and label free detection but burdensome and sophisticated. Recent studies of interest rely more on the application of nanomaterial (for indirect biochemical assays) than direct testing for in situ discrimination of the morphology of normal and cancerous cells. This review will be devoted to a description of the most recent developments of polarized light-based cancer cell/biomarker detection devices. These devices mostly operate based on a degree of polarization (DOP) and angle of polarization (AOP) of light parameters in separate devices. The main aim of this review is to provide an in-depth insight into the future use of device that measures the AOP in a single integrated device for cancer cell/tissue detection. © 2001-2012 IEEE. Institute of Electrical and Electronics Engineers (IEEE) 2019 Article PeerReviewed Tukimin, Siti Nurainie and Karman, Salmah and Ahmad, Mohd Yazed and Wan Kamarul Zaman, Wan Safwani (2019) Polarized Light-Based Cancer Cell Detection Techniques: A Review. IEEE Sensors Journal, 19 (20). pp. 9010-9025. ISSN 1530-437X, DOI https://doi.org/10.1109/JSEN.2019.2924535 <https://doi.org/10.1109/JSEN.2019.2924535>. https://doi.org/10.1109/JSEN.2019.2924535 doi:10.1109/JSEN.2019.2924535
spellingShingle R Medicine
TA Engineering (General). Civil engineering (General)
Tukimin, Siti Nurainie
Karman, Salmah
Ahmad, Mohd Yazed
Wan Kamarul Zaman, Wan Safwani
Polarized Light-Based Cancer Cell Detection Techniques: A Review
title Polarized Light-Based Cancer Cell Detection Techniques: A Review
title_full Polarized Light-Based Cancer Cell Detection Techniques: A Review
title_fullStr Polarized Light-Based Cancer Cell Detection Techniques: A Review
title_full_unstemmed Polarized Light-Based Cancer Cell Detection Techniques: A Review
title_short Polarized Light-Based Cancer Cell Detection Techniques: A Review
title_sort polarized light based cancer cell detection techniques a review
topic R Medicine
TA Engineering (General). Civil engineering (General)
work_keys_str_mv AT tukiminsitinurainie polarizedlightbasedcancercelldetectiontechniquesareview
AT karmansalmah polarizedlightbasedcancercelldetectiontechniquesareview
AT ahmadmohdyazed polarizedlightbasedcancercelldetectiontechniquesareview
AT wankamarulzamanwansafwani polarizedlightbasedcancercelldetectiontechniquesareview