Endogenous Annexin-A1 Negatively Regulates Mast Cell-Mediated Allergic Reactions

Mast cell stabilizers like cromoglycate and nedocromil are mainstream treatments for ocular allergy. Biochemical studies in vitro suggest that these drugs prevent mast cell degranulation through the release of Annexin-A1 (Anx-A1) protein. However, the direct effect of Anx-A1 gene deletion on mast ce...

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Bibliographic Details
Main Authors: Sinniah, Ajantha, Yazid, Samia, Bena, Stefania, Oliani, Sonia M., Perretti, Mauro, Flower, Rod J.
Format: Article
Published: Frontiers Media 2019
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