Small molecule grp94 inhibitors block dengue and Zika virus replication

Small molecule grp94 inhibitors block dengue and Zika virus replication

Two major flaviviruses, dengue virus (DENV) and Zika virus (ZIKV), cause severe health and economic burdens worldwide. Recently, genome-wide screenings have uncovered the importance of regulators of the Hrd1 ubiquitin ligase-mediated endoplasmic reticulum (ER)-associated degradation (ERAD) pathway f...

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Bibliographic Details
Main Authors:	Rothan, Hussin A., Zhong, Yongwang, Sanborn, Mark A., Teoh, Teow Chong, Ruan, Jingjing, Yusof, Rohana, Hang, Jun, Henderson, Mark J., Fang, Shengyun
Format:	Article
Published:	Elsevier Masson 2019
Subjects:	QR Microbiology R Medicine

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