Antibacterial Activity of Hoya Diversifolia Ethanolic Leaves Extract

The rapid emergence of resistance bacteria toward various antibiotics may associate with higher medical cost and increase mortality rate. Hoya diversifolia was used to cure skin diseases and alleviate rheumatism pain. The aim of this study is to evaluate in vitro antibacterial properties of H. diver...

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Main Authors: Ab-Rahim, Nurhidayah, Ismail, Wan Ismahanisa, Fikri Roslan, Muhammad Nabil, Hafiz Mail, Mohd, Che Lamin, Roz Azinur, Ismail, Salmah
Format: Article
Published: Oriental Scientific Publishing Company 2019
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author Ab-Rahim, Nurhidayah
Ismail, Wan Ismahanisa
Fikri Roslan, Muhammad Nabil
Hafiz Mail, Mohd
Che Lamin, Roz Azinur
Ismail, Salmah
author_facet Ab-Rahim, Nurhidayah
Ismail, Wan Ismahanisa
Fikri Roslan, Muhammad Nabil
Hafiz Mail, Mohd
Che Lamin, Roz Azinur
Ismail, Salmah
author_sort Ab-Rahim, Nurhidayah
collection UM
description The rapid emergence of resistance bacteria toward various antibiotics may associate with higher medical cost and increase mortality rate. Hoya diversifolia was used to cure skin diseases and alleviate rheumatism pain. The aim of this study is to evaluate in vitro antibacterial properties of H. diversifolia ethanolicleaves extract against several Gram positive and Gram negative bacteria. The antibacterial study was determined based on pattern of inhibition zones using disc diffusion assay and also minimal inhibitory concentration (MIC). It is shown that the extract can inhibit the growth of methicillin-resistant Staphylococcus aureus,Escherichia coliandBacillus cereus.The lowest MIC values of extract were 25 mg/mL for MRSA and E. coli as well as 100 mg/mL for B. cereus at 24 and 48 hours of incubation period. The plant had potential to act as antibacterial agent that can be applied in pharmaceutical and cosmetic fields. © 2019 Oriental Scientific Publishing Company. All rights reserved.
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spelling um.eprints-237112020-02-10T03:32:30Z http://eprints.um.edu.my/23711/ Antibacterial Activity of Hoya Diversifolia Ethanolic Leaves Extract Ab-Rahim, Nurhidayah Ismail, Wan Ismahanisa Fikri Roslan, Muhammad Nabil Hafiz Mail, Mohd Che Lamin, Roz Azinur Ismail, Salmah Q Science (General) QR Microbiology The rapid emergence of resistance bacteria toward various antibiotics may associate with higher medical cost and increase mortality rate. Hoya diversifolia was used to cure skin diseases and alleviate rheumatism pain. The aim of this study is to evaluate in vitro antibacterial properties of H. diversifolia ethanolicleaves extract against several Gram positive and Gram negative bacteria. The antibacterial study was determined based on pattern of inhibition zones using disc diffusion assay and also minimal inhibitory concentration (MIC). It is shown that the extract can inhibit the growth of methicillin-resistant Staphylococcus aureus,Escherichia coliandBacillus cereus.The lowest MIC values of extract were 25 mg/mL for MRSA and E. coli as well as 100 mg/mL for B. cereus at 24 and 48 hours of incubation period. The plant had potential to act as antibacterial agent that can be applied in pharmaceutical and cosmetic fields. © 2019 Oriental Scientific Publishing Company. All rights reserved. Oriental Scientific Publishing Company 2019 Article PeerReviewed Ab-Rahim, Nurhidayah and Ismail, Wan Ismahanisa and Fikri Roslan, Muhammad Nabil and Hafiz Mail, Mohd and Che Lamin, Roz Azinur and Ismail, Salmah (2019) Antibacterial Activity of Hoya Diversifolia Ethanolic Leaves Extract. Biomedical and Pharmacology Journal, 12 (2). pp. 857-862. ISSN 0974-6242, DOI https://doi.org/10.13005/bpj/1710 <https://doi.org/10.13005/bpj/1710>. https://doi.org/10.13005/bpj/1710 doi:10.13005/bpj/1710
spellingShingle Q Science (General)
QR Microbiology
Ab-Rahim, Nurhidayah
Ismail, Wan Ismahanisa
Fikri Roslan, Muhammad Nabil
Hafiz Mail, Mohd
Che Lamin, Roz Azinur
Ismail, Salmah
Antibacterial Activity of Hoya Diversifolia Ethanolic Leaves Extract
title Antibacterial Activity of Hoya Diversifolia Ethanolic Leaves Extract
title_full Antibacterial Activity of Hoya Diversifolia Ethanolic Leaves Extract
title_fullStr Antibacterial Activity of Hoya Diversifolia Ethanolic Leaves Extract
title_full_unstemmed Antibacterial Activity of Hoya Diversifolia Ethanolic Leaves Extract
title_short Antibacterial Activity of Hoya Diversifolia Ethanolic Leaves Extract
title_sort antibacterial activity of hoya diversifolia ethanolic leaves extract
topic Q Science (General)
QR Microbiology
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