The 4717C > G polymorphism in periplakin modulates sensitivity to EGFR inhibitors
The use of EGFR inhibitors on oral squamous cell carcinoma (OSCC) as monotherapy yielded modest clinical outcomes and therefore would benefit from biomarkers that could predict which patient subsets are likely to respond. Here, we determined the efficacy of erlotinib in OSCC cell lines, and by compa...
Main Authors: | , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Research
2019
|
Subjects: | |
Online Access: | http://eprints.um.edu.my/23887/1/s41598-019-38742-0.pdf |